Luminescent gold nanoparticles with efficient renal clearance

Chen Zhou, Michael Long, Yanping Qin, Xiankai Sun, Jie Zheng

Research output: Contribution to journalArticle

250 Citations (Scopus)

Abstract

Going to waste: Renal clearance of 2-nm glutathione-coated luminescent gold nanoparticles (GS-AuNPs) was more than 10 to 100 times better than that of the similarly sized nonluminescent AuNPs coated by bis(p-sulfonatophenyl) phenylphosphine and cysteine. Urinary excretion of the particles was imaged with X-ray computed tomography (see picture of a mouse after injection of GS-AuNPs) and luminescence techniques in real time.

Original languageEnglish (US)
Pages (from-to)3168-3172
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number14
DOIs
StatePublished - Mar 28 2011

Fingerprint

Gold
Tomography
Glutathione
Cysteine
Luminescence
Nanoparticles
X rays
bis(p-sulfonatophenyl)phenylphosphine

Keywords

  • glutathione
  • gold
  • luminescence
  • nanoparticles
  • renal clearance

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Luminescent gold nanoparticles with efficient renal clearance. / Zhou, Chen; Long, Michael; Qin, Yanping; Sun, Xiankai; Zheng, Jie.

In: Angewandte Chemie - International Edition, Vol. 50, No. 14, 28.03.2011, p. 3168-3172.

Research output: Contribution to journalArticle

Zhou, Chen ; Long, Michael ; Qin, Yanping ; Sun, Xiankai ; Zheng, Jie. / Luminescent gold nanoparticles with efficient renal clearance. In: Angewandte Chemie - International Edition. 2011 ; Vol. 50, No. 14. pp. 3168-3172.
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