Luminescent gold nanoparticles with efficient renal clearance

Chen Zhou, Michael Long, Yanping Qin, Xiankai Sun, Jie Zheng

Research output: Contribution to journalArticle

278 Scopus citations

Abstract

Going to waste: Renal clearance of 2-nm glutathione-coated luminescent gold nanoparticles (GS-AuNPs) was more than 10 to 100 times better than that of the similarly sized nonluminescent AuNPs coated by bis(p-sulfonatophenyl) phenylphosphine and cysteine. Urinary excretion of the particles was imaged with X-ray computed tomography (see picture of a mouse after injection of GS-AuNPs) and luminescence techniques in real time.

Original languageEnglish (US)
Pages (from-to)3168-3172
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number14
DOIs
StatePublished - Mar 28 2011

Keywords

  • glutathione
  • gold
  • luminescence
  • nanoparticles
  • renal clearance

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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