Abstract
Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.
| Original language | English (US) |
|---|---|
| Article number | 240 |
| Journal | Arthritis Research and Therapy |
| Volume | 13 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 28 2011 |
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ASJC Scopus subject areas
- Rheumatology
- Immunology
- Immunology and Allergy
- Medicine(all)
Cite this
Lupus nephritis : Current update. / Saxena, Ramesh; Mahajan, Tina; Mohan, Chandra.
In: Arthritis Research and Therapy, Vol. 13, No. 5, 240, 28.09.2011.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lupus nephritis
T2 - Current update
AU - Saxena, Ramesh
AU - Mahajan, Tina
AU - Mohan, Chandra
PY - 2011/9/28
Y1 - 2011/9/28
N2 - Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.
AB - Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.
UR - http://www.scopus.com/inward/record.url?scp=81255196460&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=81255196460&partnerID=8YFLogxK
U2 - 10.1186/ar3378
DO - 10.1186/ar3378
M3 - Article
C2 - 22078716
AN - SCOPUS:81255196460
VL - 13
JO - Arthritis Research and Therapy
JF - Arthritis Research and Therapy
SN - 1478-6354
IS - 5
M1 - 240
ER -