Lupus nephritis: Current update

Ramesh Saxena, Tina Mahajan, Chandra Mohan

Research output: Contribution to journalReview article

81 Scopus citations

Abstract

Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.

Original languageEnglish (US)
Article number240
JournalArthritis Research and Therapy
Volume13
Issue number5
DOIs
StatePublished - Sep 28 2011

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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