Lupus nephritis: Current update

Ramesh Saxena; Tina Mahajan; Chandra Mohan

doi:10.1186/ar3378

Lupus nephritis: Current update

Ramesh Saxena, Tina Mahajan, Chandra Mohan

Research output: Contribution to journal › Review article › peer-review

94 Scopus citations

Abstract

Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.

Original language	English (US)
Article number	240
Journal	Arthritis Research and Therapy
Volume	13
Issue number	5
DOIs	https://doi.org/10.1186/ar3378
State	Published - Sep 28 2011

ASJC Scopus subject areas

Rheumatology
Immunology and Allergy
Immunology

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abstract = "Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.",

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N2 - Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.

AB - Lupus nephritis is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. The general consensus is that 60% of lupus patients will develop clinically relevant nephritis at some time in the course of their illness. Prompt recognition and treatment of renal disease is important, as early response to therapy is correlated with better outcome. The present review summarizes our current understanding of the pathogenic mechanisms underlying lupus nephritis and how the disease is currently diagnosed and treated.

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Lupus nephritis: Current update

Abstract

ASJC Scopus subject areas

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