Lymphocyte subpopulations in Kawasaki disease

K. Shannon, C. W. Fink, G. R. Buchanan, M. Punaro, P. Stastny

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The relative percentages of subpopulations of peripheral T lymphocytes in children with Kawasaki Disease (KD) was investigated using matched antibodies directed against the T3, T4 and T8 antigens. The percentage of B cells was determined with antibodies against human surface immunoglobulins. Subjects were six children with acute KD who were compared to normal, age-matched controls. The percentage of peripheral lymphocytes positive for OKT3 was 61% for KD children and 64% for controls; for OKT4 they were 41% and 44% respectively and for OKT8 both were 19%. The B cell percentages were 13% in KD and 11% in controls. Thus no abnormalities in the distribution of lymphocyte subtypes in children with KD was found. Previous studies of immune function in KD are reviewed.

Original languageEnglish (US)
Pages (from-to)59-62
Number of pages4
JournalClinical and experimental rheumatology
Volume1
Issue number1
StatePublished - Dec 1 1983

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    Shannon, K., Fink, C. W., Buchanan, G. R., Punaro, M., & Stastny, P. (1983). Lymphocyte subpopulations in Kawasaki disease. Clinical and experimental rheumatology, 1(1), 59-62.