Lysine vasopressin in Alzheimer disease

R. Durso, P. Fedio, P. Brouwers, C. Cox, A. J. Martin, S. A. Ruggieri, C. A. Tamminga, T. N. Chase

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The effect of lysine vasopressin on memory and cognitive deficits in Alzheimer disease was investigated. In a double-blind study, seven patients were given 16 units of lysine vasopressin per day for 10 days and were compared with seven different patients receiving placebo. No significant differences in performance between the vasopressin and placebo-treated groups was found in tests designed to evaluate learning, memory, and perception. However, significantly greater improvement in reaction time was seen in the vasopressin-treated group, although this effect was delayed and may have been contributed to by factors other than drug activity.

Original languageEnglish (US)
Pages (from-to)674-677
Number of pages4
JournalNeurology
Volume32
Issue number6
StatePublished - 1982

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Lypressin
Vasopressins
Alzheimer Disease
Placebos
Memory Disorders
Double-Blind Method
Reaction Time
Learning
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Durso, R., Fedio, P., Brouwers, P., Cox, C., Martin, A. J., Ruggieri, S. A., ... Chase, T. N. (1982). Lysine vasopressin in Alzheimer disease. Neurology, 32(6), 674-677.

Lysine vasopressin in Alzheimer disease. / Durso, R.; Fedio, P.; Brouwers, P.; Cox, C.; Martin, A. J.; Ruggieri, S. A.; Tamminga, C. A.; Chase, T. N.

In: Neurology, Vol. 32, No. 6, 1982, p. 674-677.

Research output: Contribution to journalArticle

Durso, R, Fedio, P, Brouwers, P, Cox, C, Martin, AJ, Ruggieri, SA, Tamminga, CA & Chase, TN 1982, 'Lysine vasopressin in Alzheimer disease', Neurology, vol. 32, no. 6, pp. 674-677.
Durso R, Fedio P, Brouwers P, Cox C, Martin AJ, Ruggieri SA et al. Lysine vasopressin in Alzheimer disease. Neurology. 1982;32(6):674-677.
Durso, R. ; Fedio, P. ; Brouwers, P. ; Cox, C. ; Martin, A. J. ; Ruggieri, S. A. ; Tamminga, C. A. ; Chase, T. N. / Lysine vasopressin in Alzheimer disease. In: Neurology. 1982 ; Vol. 32, No. 6. pp. 674-677.
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