Macrodactyly: decision-making and surgery timing

Marybeth Ezaki, Terri Beckwith, Scott N Oishi

Research output: Contribution to journalReview article


Macrodactyly is a rare condition in which fingers, hands or limb growth is unregulated, resulting in overgrowth of tissues in the affected extremities. It is critical to properly assess these extremities for signalling pathway, psychological impact and potential surgical intervention, to achieve the best possible outcome for each patient. Treatment approaches can vary, and patient and family expectations weigh heavily on care complexity. Common surgical procedures may include epiphysiodeses, osteotomies, debulking procedures, carpal tunnel releases, toe transfers and amputations. The selection and timing of these surgeries is a vital component of the approach, as delayed healing and excessive scarring may occur. The purpose of this review is to assist in the navigation of decision-making and surgical timing for patients presenting with overgrowth manifesting itself as macrodactyly.

Original languageEnglish (US)
Pages (from-to)32-42
Number of pages11
JournalJournal of Hand Surgery: European Volume
Issue number1
StatePublished - Jan 1 2019


  • Macrodactyly
  • overgrowth
  • paediatric orthopaedics
  • patient care
  • PIK3CA
  • surgical care

ASJC Scopus subject areas

  • Surgery

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