Magnetic field correlation imaging

Jens H. Jensen, Ramesh Chandra, Anita Ramani, Hanzhang Lu, Glyn Johnson, Sang Pil Lee, Kyle Kaczynski, Joseph A. Helpern

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

A magnetic resonance imaging (MRI) method is presented for estimating the magnetic field correlation (MFC) associated with magnetic field inhomogeneities (MFIs) within biological tissues. The method utilizes asymmetric spin echoes and is based on a detailed theory for the effect of MFIs on nuclear magnetic resonance (NMR) signal decay. The validity of the method is supported with results from phantom experiments at 1.5 and 3 T, and human brain images obtained at 3 T are shown to demonstrate the method's feasibility. The preliminary results suggest that MFC imaging may be useful for the quantitative assessment of iron within the brain.

Original languageEnglish (US)
Pages (from-to)1350-1361
Number of pages12
JournalMagnetic resonance in medicine
Volume55
Issue number6
DOIs
StatePublished - Jun 2006

Keywords

  • Asymmetric spin echo
  • Brain
  • Iron
  • MRI
  • Magnetic field inhomogeneities

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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