Magnetic resonance imaging diagnosis of severe fetal renal anomalies

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Abstract

Objective: The purpose of this study was to describe magnetic resonance imaging (MRI) findings in fetuses with severe renal anomalies. Study Design: This was a case-control study that compared MRI findings in fetuses with suspected severe renal anomalies with gestational age-matched control fetuses. MRI was performed with T2-weighted single-shot fast-spin echo sequences. Each MRI was reviewed by an investigator who was blinded to clinical information. Results: There were 2 cases of bilateral renal agenesis, 2 cases if bilateral multicystic dysplastic kidney disease, 2 cases if unilateral renal agenesis and contralateral multicystic dysplastic kidney disease, 2 cases if polycystic kidney disease, and 2 cases of early membrane rupture/normal kidneys. Fetuses with lethal renal anomalies had a characteristic bladder appearance (signal void [dark]), whereas control fetuses had bright signal in both bladder and renal pelvis (P < .001). Both cases of early membrane rupture/normal kidneys had bright bladder signal, but 1 case did not have bright signal in the renal pelvis. Conclusion: Fetuses with lethal renal anomalies had signal void in the bladder region on MRI.

Original languageEnglish (US)
JournalAmerican Journal of Obstetrics and Gynecology
Volume198
Issue number3
DOIs
StatePublished - Mar 2008

Fingerprint

Fetus
Magnetic Resonance Imaging
Kidney
Urinary Bladder
Multicystic Dysplastic Kidney
Kidney Pelvis
Kidney Diseases
Rupture
Autosomal Dominant Polycystic Kidney
Membranes
Gestational Age
Case-Control Studies
Research Personnel
Hereditary renal agenesis

Keywords

  • fetal renal anomaly
  • magnetic resonance imaging

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

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title = "Magnetic resonance imaging diagnosis of severe fetal renal anomalies",
abstract = "Objective: The purpose of this study was to describe magnetic resonance imaging (MRI) findings in fetuses with severe renal anomalies. Study Design: This was a case-control study that compared MRI findings in fetuses with suspected severe renal anomalies with gestational age-matched control fetuses. MRI was performed with T2-weighted single-shot fast-spin echo sequences. Each MRI was reviewed by an investigator who was blinded to clinical information. Results: There were 2 cases of bilateral renal agenesis, 2 cases if bilateral multicystic dysplastic kidney disease, 2 cases if unilateral renal agenesis and contralateral multicystic dysplastic kidney disease, 2 cases if polycystic kidney disease, and 2 cases of early membrane rupture/normal kidneys. Fetuses with lethal renal anomalies had a characteristic bladder appearance (signal void [dark]), whereas control fetuses had bright signal in both bladder and renal pelvis (P < .001). Both cases of early membrane rupture/normal kidneys had bright bladder signal, but 1 case did not have bright signal in the renal pelvis. Conclusion: Fetuses with lethal renal anomalies had signal void in the bladder region on MRI.",
keywords = "fetal renal anomaly, magnetic resonance imaging",
author = "Hawkins, {J. Seth} and Dashe, {Jodi S.} and Twickler, {Diane M.}",
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AU - Dashe, Jodi S.

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N2 - Objective: The purpose of this study was to describe magnetic resonance imaging (MRI) findings in fetuses with severe renal anomalies. Study Design: This was a case-control study that compared MRI findings in fetuses with suspected severe renal anomalies with gestational age-matched control fetuses. MRI was performed with T2-weighted single-shot fast-spin echo sequences. Each MRI was reviewed by an investigator who was blinded to clinical information. Results: There were 2 cases of bilateral renal agenesis, 2 cases if bilateral multicystic dysplastic kidney disease, 2 cases if unilateral renal agenesis and contralateral multicystic dysplastic kidney disease, 2 cases if polycystic kidney disease, and 2 cases of early membrane rupture/normal kidneys. Fetuses with lethal renal anomalies had a characteristic bladder appearance (signal void [dark]), whereas control fetuses had bright signal in both bladder and renal pelvis (P < .001). Both cases of early membrane rupture/normal kidneys had bright bladder signal, but 1 case did not have bright signal in the renal pelvis. Conclusion: Fetuses with lethal renal anomalies had signal void in the bladder region on MRI.

AB - Objective: The purpose of this study was to describe magnetic resonance imaging (MRI) findings in fetuses with severe renal anomalies. Study Design: This was a case-control study that compared MRI findings in fetuses with suspected severe renal anomalies with gestational age-matched control fetuses. MRI was performed with T2-weighted single-shot fast-spin echo sequences. Each MRI was reviewed by an investigator who was blinded to clinical information. Results: There were 2 cases of bilateral renal agenesis, 2 cases if bilateral multicystic dysplastic kidney disease, 2 cases if unilateral renal agenesis and contralateral multicystic dysplastic kidney disease, 2 cases if polycystic kidney disease, and 2 cases of early membrane rupture/normal kidneys. Fetuses with lethal renal anomalies had a characteristic bladder appearance (signal void [dark]), whereas control fetuses had bright signal in both bladder and renal pelvis (P < .001). Both cases of early membrane rupture/normal kidneys had bright bladder signal, but 1 case did not have bright signal in the renal pelvis. Conclusion: Fetuses with lethal renal anomalies had signal void in the bladder region on MRI.

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