Maintaining Hematopoietic Stem Cells in the Vascular Niche

Mark J. Kiel, Sean J. Morrison

Research output: Contribution to journalShort survey

114 Scopus citations

Abstract

In this issue of Immunity, Sugiyama et al. (2006) provide evidence that most bone-marrow hematopoietic stem cells (HSCs) reside in vascular niches containing reticular cells that secrete CXCL12, a chemokine that promotes HSC maintenance.

Original languageEnglish (US)
Pages (from-to)862-864
Number of pages3
JournalImmunity
Volume25
Issue number6
DOIs
StatePublished - Dec 1 2006

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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