Major Adverse Cardiac Events at Follow-Up After Bare-Metal Stenting Versus Drug-Eluting Stenting in ST-Elevated Myocardial Infarction

Bredy Pierre-Louis, Wilbert S. Aronow, Chandrasekar Palaniswamy, Tarunjit Singh, Chul Ahn, Amit Asija, Melvin B. Weiss, Kumar Kalapatapu, Anthony L. Pucillo, Craig E. Monsen

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

After thrombolytic therapy with tenecteplase for ST-segment elevation acute myocardial infarction, 376 patients were transferred from their hospital to Westchester Medical Center for percutaneous coronary intervention with stenting. Of 376 patients, 102 (27%) received bare-metal stents and 274 (73%) received drug-eluting stents with sirolimus-eluting or paclitaxel-eluting stents. At 43 months of follow-up, major adverse cardiac events occurred in 25 (25%) of 102 patients treated with bare-metal stents versus 40 (15%) of 274 patients treated with drug-eluting stents (p = 0.024). Cox regression analysis showed that significant independent prognostic factors for major adverse cardiac events were previous coronary artery bypass surgery (hazard ratio 2.2, p = 0.019), width of stent (hazard ratio 0.44, p = 0.006), and bare-metal stent (hazard ratio 1.8, p = 0.019). In conclusion, patients with bare-metal stents had a 1.8 times greater risk of developing major adverse cardiac events than did those using drug-eluting stents after controlling the confounding effects of previous coronary artery bypass surgery and stent width.

Original languageEnglish (US)
Pages (from-to)1672-1674
Number of pages3
JournalAmerican Journal of Cardiology
Volume103
Issue number12
DOIs
StatePublished - Jun 15 2009

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Pierre-Louis, B., Aronow, W. S., Palaniswamy, C., Singh, T., Ahn, C., Asija, A., Weiss, M. B., Kalapatapu, K., Pucillo, A. L., & Monsen, C. E. (2009). Major Adverse Cardiac Events at Follow-Up After Bare-Metal Stenting Versus Drug-Eluting Stenting in ST-Elevated Myocardial Infarction. American Journal of Cardiology, 103(12), 1672-1674. https://doi.org/10.1016/j.amjcard.2009.02.016