Major adverse cardiac events at long-term follow-up in patients treated with single versus multiple stents during single-vessel percutaneous coronary intervention

Wilbert S. Aronow, Rishi Sukhija, Chandrasekar Palaniswamy, Tarunjit Singh, Chul Ahn, Kumar Kalapatapu, Bhavna Chaturvedi, Anthony L. Pucillo, Carmine Sorbera, Priyanka Kakar, Melvin B. Weiss, Vimal Mehta, Craig E. Monsen

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Although insertion of multiple stents into a single coronary vessel during single-vessel percutaneous coronary intervention (PCI) is common, there are no data on long-term occurrence of major adverse cardiac events (MACE) in patients treated with multiple stents versus a single stent. Methods: The incidence of MACE (death, myocardial infarction, or target vessel revascularization) during long-term follow-up was investigated in 634 patients who underwent single-vessel PCI. Of the 634 patients, 319 (50%) had a single stent, and 315 (50%) had multiple stents inserted. Stepwise Cox regression analyses were performed to identify significant independent prognostic factors for MACE. Results: At 47-month follow-up, MACE occurred in 61 of 319 patients (19%) who had a single stent versus in 57 of 315 patients (18%) who had multiple stents (P not significant). Significant independent predictors of MACE were use of vein grafts (hazard ratio = 1.94; 95% CI, 1.24-3.03; P = 0.0038) and use of drug-eluting stents (hazard ratio = 0.49; 95% CI, 0.34-0.72; P = 0.0002). Conclusions: At long-term follow-up of single-vessel PCI, the incidence of MACE was similar in patients with multiple or single stents inserted even after controlling for the length of stents. (J Interven Cardiol 2009;22:427-430)

Original languageEnglish (US)
Pages (from-to)427-430
Number of pages4
JournalJournal of Interventional Cardiology
Volume22
Issue number5
DOIs
StatePublished - Oct 1 2009

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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