Management of hereditary thyroid cancer in children

Michael A. Skinner

doi:10.1016/S0960-7404(03)00033-1

Management of hereditary thyroid cancer in children

Michael A. Skinner

Surgery

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Hereditary thyroid cancer in childhood occurs in the setting of Multiple Endocrine Neoplasia types 2A and 2B, and familial medullary thyroid carcinoma, FMTC. Prophylactic thyroidectomy in childhood has been recommended in patients found to have inherited mutations in the RET protooncogene, to prevent the development of medullary thyroid carcinoma. In this report are presented the clinical and genetic aspects of hereditary thyroid cancer in children, as well as surgical recommendations and medium-term outcome results.

Original language	English (US)
Pages (from-to)	101-104
Number of pages	4
Journal	Surgical Oncology
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/S0960-7404(03)00033-1
State	Published - Aug 2003

Keywords

Medullary thyroid carcinoma
Multiple endocrine neoplasia
RET protooncogene

ASJC Scopus subject areas

Surgery
Oncology

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10.1016/S0960-7404(03)00033-1

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AB - Hereditary thyroid cancer in childhood occurs in the setting of Multiple Endocrine Neoplasia types 2A and 2B, and familial medullary thyroid carcinoma, FMTC. Prophylactic thyroidectomy in childhood has been recommended in patients found to have inherited mutations in the RET protooncogene, to prevent the development of medullary thyroid carcinoma. In this report are presented the clinical and genetic aspects of hereditary thyroid cancer in children, as well as surgical recommendations and medium-term outcome results.

KW - Medullary thyroid carcinoma

KW - Multiple endocrine neoplasia

KW - RET protooncogene

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Management of hereditary thyroid cancer in children

Abstract

Keywords

ASJC Scopus subject areas

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