Management of hypertensive chronic kidney disease: role of calcium channel blockers.

Research output: Contribution to journalReview article

18 Scopus citations

Abstract

Both the prevalence and incidence of end-stage renal disease have been increasing in the United States over the past two decades. Diabetes and hypertension are the attributable causes for more than three fourths of all new cases of end-stage renal disease. The overwhelming majority of diabetics with nephropathy are hypertensive, and lowering blood pressure is indicated in all patients with chronic kidney disease because of the increased risk for cardiovascular morbidity and mortality. Multiple studies indicate that reaching goal systolic blood pressure in patients with chronic kidney disease generally requires three to four antihypertensive agents. A number of medication combinations can effectively reduce blood pressure in the chronic kidney disease patient. In this regard, adding a calcium channel blocker to an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker helps in reaching goal blood pressure while preserving renal function in both diabetics and nondiabetics with proteinuria.

Original languageEnglish (US)
Pages (from-to)15-20
Number of pages6
JournalJournal of clinical hypertension (Greenwich, Conn.)
Volume7
Issue number4 Suppl 1
DOIs
StatePublished - Apr 2005

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Management of hypertensive chronic kidney disease: role of calcium channel blockers.'. Together they form a unique fingerprint.

  • Cite this