Management of Infectious Complications in the Critically Ill Obese Patient

Kristin Turza Campbell; Laura H. Rosenberger; Amani D. Politano; Tjasa Hranjec; Robert G. Sawyer

doi:10.1002/9781119962083.ch10

Management of Infectious Complications in the Critically Ill Obese Patient

Kristin Turza Campbell, Laura H. Rosenberger, Amani D. Politano, Tjasa Hranjec, Robert G. Sawyer

Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Managing infectious complications in obese critically ill patients presents unique challenges and is associated with significant cost to the health care industry. Generally, obese patients tend to have a higher incidence of blood-stream, catheter-related, and surgical-site infections. Physiologically, obesity is a chronic inflammatory state, which may result in an exaggerated immune response to sepsis. Adipocytes release cytokines and adipokines that have been implicated in the proinflammatory phenotype of obesity. Not only is aggressive prevention of infection by a multidisciplinary team valuable, but narrowing antibiotics to target the organisms present is fundamental in obese patients.

Original language	English (US)
Title of host publication	Critical Care Management of the Obese Patient
Publisher	Wiley-Blackwell
Pages	83-92
Number of pages	10
ISBN (Print)	9780470655900
DOIs	https://doi.org/10.1002/9781119962083.ch10
State	Published - Apr 19 2012

Keywords

Antibiotics
Catheter-related infections
Infection
Obesity
Recommendations
Surgical-site infection

ASJC Scopus subject areas

General Medicine

Access to Document

10.1002/9781119962083.ch10

Cite this

@inbook{03d3ea60c46249e2b35c4d5d63465bab,

title = "Management of Infectious Complications in the Critically Ill Obese Patient",

abstract = "Managing infectious complications in obese critically ill patients presents unique challenges and is associated with significant cost to the health care industry. Generally, obese patients tend to have a higher incidence of blood-stream, catheter-related, and surgical-site infections. Physiologically, obesity is a chronic inflammatory state, which may result in an exaggerated immune response to sepsis. Adipocytes release cytokines and adipokines that have been implicated in the proinflammatory phenotype of obesity. Not only is aggressive prevention of infection by a multidisciplinary team valuable, but narrowing antibiotics to target the organisms present is fundamental in obese patients.",

keywords = "Antibiotics, Catheter-related infections, Infection, Obesity, Recommendations, Surgical-site infection",

author = "{Turza Campbell}, Kristin and Rosenberger, {Laura H.} and Politano, {Amani D.} and Tjasa Hranjec and Sawyer, {Robert G.}",

year = "2012",

month = apr,

day = "19",

doi = "10.1002/9781119962083.ch10",

language = "English (US)",

isbn = "9780470655900",

pages = "83--92",

booktitle = "Critical Care Management of the Obese Patient",

publisher = "Wiley-Blackwell",

}

TY - CHAP

T1 - Management of Infectious Complications in the Critically Ill Obese Patient

AU - Turza Campbell, Kristin

AU - Rosenberger, Laura H.

AU - Politano, Amani D.

AU - Hranjec, Tjasa

AU - Sawyer, Robert G.

PY - 2012/4/19

Y1 - 2012/4/19

N2 - Managing infectious complications in obese critically ill patients presents unique challenges and is associated with significant cost to the health care industry. Generally, obese patients tend to have a higher incidence of blood-stream, catheter-related, and surgical-site infections. Physiologically, obesity is a chronic inflammatory state, which may result in an exaggerated immune response to sepsis. Adipocytes release cytokines and adipokines that have been implicated in the proinflammatory phenotype of obesity. Not only is aggressive prevention of infection by a multidisciplinary team valuable, but narrowing antibiotics to target the organisms present is fundamental in obese patients.

AB - Managing infectious complications in obese critically ill patients presents unique challenges and is associated with significant cost to the health care industry. Generally, obese patients tend to have a higher incidence of blood-stream, catheter-related, and surgical-site infections. Physiologically, obesity is a chronic inflammatory state, which may result in an exaggerated immune response to sepsis. Adipocytes release cytokines and adipokines that have been implicated in the proinflammatory phenotype of obesity. Not only is aggressive prevention of infection by a multidisciplinary team valuable, but narrowing antibiotics to target the organisms present is fundamental in obese patients.

KW - Antibiotics

KW - Catheter-related infections

KW - Infection

KW - Obesity

KW - Recommendations

KW - Surgical-site infection

UR - http://www.scopus.com/inward/record.url?scp=84886811009&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886811009&partnerID=8YFLogxK

U2 - 10.1002/9781119962083.ch10

DO - 10.1002/9781119962083.ch10

M3 - Chapter

AN - SCOPUS:84886811009

SN - 9780470655900

SP - 83

EP - 92

BT - Critical Care Management of the Obese Patient

PB - Wiley-Blackwell

ER -

Management of Infectious Complications in the Critically Ill Obese Patient

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this