Management of intrinsic sphincteric deficiency in women

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Purpose: We reviewed treatment options for intrinsic sphincteric deficiency in women with an emphasis on safety and efficacy. Materials and Methods: Using MEDLINE, we comprehensively reviewed literature relevant to management of intrinsic sphincteric deficiency. We focused on peer reviewed articles from 1995 through December 2001 with older articles included for historical purposes. Results: Past and current treatment options for intrinsic sphincteric deficiency fall into the 3 categories of urethral bulking agents, slings and artificial urinary sphincter. The autologous fascial pubovaginal sling continues to be the gold standard but newer sling materials are promising. Less invasive therapies with acceptable efficacy and safety profiles are still needed. Conclusions: Improved understanding of the continence mechanism may lead to new and improved treatment modalities for intrinsic sphincteric deficiency. However, it will be impossible to compare these treatment options with past treatment unless long-term, randomized, multicenter trials with specific definitions of cure and failure are conducted.

Original languageEnglish (US)
Pages (from-to)1662-1669
Number of pages8
JournalJournal of Urology
Volume169
Issue number5
DOIs
StatePublished - May 1 2003

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Therapeutics
Artificial Urinary Sphincter
Safety
MEDLINE
Multicenter Studies

Keywords

  • Artificial
  • Stress
  • Therapeutics
  • Urinary incontinence
  • Urinary sphincter

ASJC Scopus subject areas

  • Urology

Cite this

Management of intrinsic sphincteric deficiency in women. / Wilson, Tracey S.; Lemack, Gary E.; Zimmern, Philippe E.

In: Journal of Urology, Vol. 169, No. 5, 01.05.2003, p. 1662-1669.

Research output: Contribution to journalArticle

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