Management of perioperative myocardial infarction in noncardiac surgical patients

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Abstract

Perioperative myocardial infarction (PMI) is a major cause of morbidity and mortality in patients undergoing noncardiac surgery. The incidence of PMI varies depending on the method used for diagnosis and is likely to increase as the population ages. Studies have examined different methods for prevention of myocardial infarction (MI), including the use of perioperative β-blockers, α2-agonists, and statin therapy. However, few studies have focused on the treatment of PMI. Current therapy for acute MI generally involves anticoagulation and antiplatelet therapy, raising the potential for surgical site hemorrhage in this population. This article reviews the possible mechanisms, diagnosis, and treatment options for MI in the surgical setting. We also suggest algorithms for treatment.

Original languageEnglish (US)
Pages (from-to)584-596
Number of pages13
JournalChest
Volume130
Issue number2
DOIs
Publication statusPublished - Aug 2006

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Keywords

  • Anticoagulation
  • Myocardial ischemia
  • Noncardiac surgery
  • Percutaneous coronary intervention
  • Perioperative myocardial infarction
  • Platelet inhibitors

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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