Management of Stage II Germ Cell Tumors

Rashed A. Ghandour, Nirmish Singla, Aditya Bagrodia

Research output: Contribution to journalReview article

Abstract

There are several treatment approaches for stage II germ cell tumors (GCTs), and a thorough understanding of the staging classification and histologic differences in tumor biology and therapeutic responsiveness is critical to determine an effective, multimodal management strategy that involves urologists, medical oncologists, and radiation oncologists. This article discusses contemporary management strategies for stage II GCTs, including chemotherapy, radiotherapy, retroperitoneal lymph node dissection (RPLND), and surveillance. Patient selection, histology, and extent of lymphadenopathy drive management, and, as both treatment and detection strategies continue to emerge and be refined, the management of patients with stage II GCT continues to evolve.

Original languageEnglish (US)
JournalUrologic Clinics of North America
DOIs
StatePublished - Jan 1 2019

Keywords

  • Chemotherapy
  • Germ cell tumor
  • Nonseminoma
  • Retroperitoneal lymph node dissection
  • Seminoma

ASJC Scopus subject areas

  • Urology

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