Mapping cardiac fiber orientations from high-resolution DTI to high-frequency 3D ultrasound

Xulei Qin, Silun Wang, Ming Shen, Xiaodong Zhang, Mary B. Wagner, Baowei Fei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations

Abstract

The orientation of cardiac fibers affects the anatomical, mechanical, and electrophysiological properties of the heart. Although echocardiography is the most common imaging modality in clinical cardiac examination, it can only provide the cardiac geometry or motion information without cardiac fiber orientations. If the patienta's cardiac fiber orientations can be mapped to his/her echocardiography images in clinical examinations, it may provide quantitative measures for diagnosis, personalized modeling, and image-guided cardiac therapies. Therefore, this project addresses the feasibility of mapping personalized cardiac fiber orientations to three-dimensional (3D) ultrasound image volumes. First, the geometry of the heart extracted from the MRI is translated to 3D ultrasound by rigid and deformable registration. Deformation fields between both geometries from MRI and ultrasound are obtained after registration. Three different deformable registration methods were utilized for the MRI-ultrasound registration. Finally, the cardiac fiber orientations imaged by DTI are mapped to ultrasound volumes based on the extracted deformation fields. Moreover, this study also demonstrated the ability to simulate electricity activations during the cardiac resynchronization therapy (CRT) process. The proposed method has been validated in two rat hearts and three canine hearts. After MRI/ultrasound image registration, the Dice similarity scores were more than 90% and the corresponding target errors were less than 0.25 mm. This proposed approach can provide cardiac fiber orientations to ultrasound images and can have a variety of potential applications in cardiac imaging.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2014
Subtitle of host publicationImage-Guided Procedures, Robotic Interventions, and Modeling
PublisherSPIE
ISBN (Print)9780819498298
DOIs
StatePublished - Jan 1 2014
Externally publishedYes
EventMedical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, CA, United States
Duration: Feb 18 2014Feb 20 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9036
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CitySan Diego, CA
Period2/18/142/20/14

Keywords

  • 3D ultrasound
  • Cardiac fiber orientations
  • Deformable image registration
  • Magnetic resonance imaging (MRI)
  • diffusion tensor imaging (DTI)
  • heart imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Qin, X., Wang, S., Shen, M., Zhang, X., Wagner, M. B., & Fei, B. (2014). Mapping cardiac fiber orientations from high-resolution DTI to high-frequency 3D ultrasound. In Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling [90361O] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9036). SPIE. https://doi.org/10.1117/12.2043821