Regions of the antigen d flagellin of Salmonella muenchen capable of causing the proliferation of repolymerized d flagellin-primed T cells were delineated by using dodecameric peptides. Three areas causing substantial DNA replication were identified, together with five areas eliciting less response. On the basis of known salmonellar flagellin structure, the major areas were located in highly conserved regions of the molecule.
ASJC Scopus subject areas
- Infectious Diseases