Maxillary sinus melanoma as the presenting feature of Carney complex

Matthew W. Ryan, Samuel Cunningham, Shu Yuan Xiao

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

We present a case of a large maxillary sinus tumor in a 6-year-old boy, immunohistologically indistinguishable from a malignant melanoma, that led to the diagnosis of Carney complex. The Carney complex is an autosomal dominant disorder characterized by mucocutaneous pigmented lesions and neoplasia of multiple endocrine glands and is usually due to an inactivating mutation of the gene for the protein kinase A regulatory subunit 1A. The Carney complex has characteristic head and neck manifestations that can point to the diagnosis of this potentially lethal condition.

Original languageEnglish (US)
Pages (from-to)405-408
Number of pages4
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume72
Issue number3
DOIs
StatePublished - Mar 1 2008

Keywords

  • Carney complex
  • Maxillary sinus
  • Mucosal melanoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Otorhinolaryngology

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