MC-SleepNet: Large-scale Sleep Stage Scoring in Mice by Deep Neural Networks

Masato Yamabe, Kazumasa Horie, Hiroaki Shiokawa, Hiromasa Funato, Masashi Yanagisawa, Hiroyuki Kitagawa

Research output: Contribution to journalArticle

Abstract

Automated sleep stage scoring for mice is in high demand for sleep research, since manual scoring requires considerable human expertise and efforts. The existing automated scoring methods do not provide the scoring accuracy required for practical use. In addition, the performance of such methods has generally been evaluated using rather small-scale datasets, and their robustness against individual differences and noise has not been adequately verified. This research proposes a novel automated scoring method named “MC-SleepNet”, which combines two types of deep neural networks. Then, we evaluate its performance using a large-scale dataset that contains 4,200 biological signal records of mice. The experimental results show that MC-SleepNet can automatically score sleep stages with an accuracy of 96.6% and kappa statistic of 0.94. In addition, we confirm that the scoring accuracy does not significantly decrease even if the target biological signals are noisy. These results suggest that MC-SleepNet is very robust against individual differences and noise. To the best of our knowledge, evaluations using such a large-scale dataset (containing 4,200 records) and high scoring accuracy (96.6%) have not been reported in previous related studies.

Original languageEnglish (US)
Article number15793
JournalScientific reports
Volume9
Issue number1
DOIs
StatePublished - Dec 1 2019

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Sleep Stages
Individuality
Noise
Research Design
Research
Sleep
Datasets

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MC-SleepNet : Large-scale Sleep Stage Scoring in Mice by Deep Neural Networks. / Yamabe, Masato; Horie, Kazumasa; Shiokawa, Hiroaki; Funato, Hiromasa; Yanagisawa, Masashi; Kitagawa, Hiroyuki.

In: Scientific reports, Vol. 9, No. 1, 15793, 01.12.2019.

Research output: Contribution to journalArticle

Yamabe, Masato ; Horie, Kazumasa ; Shiokawa, Hiroaki ; Funato, Hiromasa ; Yanagisawa, Masashi ; Kitagawa, Hiroyuki. / MC-SleepNet : Large-scale Sleep Stage Scoring in Mice by Deep Neural Networks. In: Scientific reports. 2019 ; Vol. 9, No. 1.
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