Mean body temperature does not modulate eccrine sweat rate during upright tilt

Thad E. Wilson, Jian Cui, Craig G. Crandall

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Conflicting reports exist about the role of baroreflexes in efferent control of eccrine sweat rate. These conflicting reports may be due to differing mean body temperatures between studies. The purpose of this project was to test the hypothesis that mean body temperature modulates the effect of head-up tilt on sweat rate and skin sympathetic nerve activity (SSNA). To address this question, mean body temperature (0.9 · internal temperature + 0.1 · mean skin temperature), SSNA (microneurography of peroneal nerve, n = 8), and sweat rate (from an area innervated by the peroneal nerve and from two forearm sites, one perfused with neostigmine to augment sweating at lower mean body temperatures and the second with the vehicle, n = 12) were measured in 13 subjects during multiple 30° head-up tilts during whole body heating. At the end of the heat stress, mean body temperature (36.8 ± 0.1 to 38.0 ± 0.1 °C) and sweat rate at all sites were significantly elevated. No significant correlations were observed between mean body temperature and the change in SSNA during head-up tilt (r = 0.07; P = 0.62), sweating within the innervated area (r = 0.06; P = 0.56), sweating at the neostigmine treated site (r = 0.04; P = 0.69), or sweating at the control site (r = 0.01; P = 0.94). Also, for each tilt throughout the heat stress, there were no significant differences in sweat rate (final tilt sweat rates were 0.69 ± 0.11 and 0.68 ± 0.11 mg · cm-2 · min-1 within the innervated area; 1.04 ± 0.16 and 1.06 ± 0.16 mg · cm-2 · min-1 at the neostigmine-treated site; and 0.85 ± 0.15 and 0.85 ± 0.15 mg · cm-2 · min-1 at the control site, for supine and tilf, respectively). Hence, these data indicate that mean body temperature does not modulate eccrine sweat rate during baroreceptor unloading induced via 30° head-up tilt.

Original languageEnglish (US)
Pages (from-to)1207-1212
Number of pages6
JournalJournal of Applied Physiology
Volume98
Issue number4
DOIs
StatePublished - Apr 2005

Fingerprint

Sweat
Body Temperature
Sweating
Neostigmine
Head
Peroneal Nerve
Skin
Hot Temperature
Body Temperature Changes
Pressoreceptors
Skin Temperature
Baroreflex
Forearm
Heating
Temperature

Keywords

  • Baroreceptor unloading
  • Microneurography
  • Whole body heating

ASJC Scopus subject areas

  • Physiology
  • Endocrinology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Mean body temperature does not modulate eccrine sweat rate during upright tilt. / Wilson, Thad E.; Cui, Jian; Crandall, Craig G.

In: Journal of Applied Physiology, Vol. 98, No. 4, 04.2005, p. 1207-1212.

Research output: Contribution to journalArticle

@article{e75f0d822f1349bd807cd48998b44cd8,
title = "Mean body temperature does not modulate eccrine sweat rate during upright tilt",
abstract = "Conflicting reports exist about the role of baroreflexes in efferent control of eccrine sweat rate. These conflicting reports may be due to differing mean body temperatures between studies. The purpose of this project was to test the hypothesis that mean body temperature modulates the effect of head-up tilt on sweat rate and skin sympathetic nerve activity (SSNA). To address this question, mean body temperature (0.9 · internal temperature + 0.1 · mean skin temperature), SSNA (microneurography of peroneal nerve, n = 8), and sweat rate (from an area innervated by the peroneal nerve and from two forearm sites, one perfused with neostigmine to augment sweating at lower mean body temperatures and the second with the vehicle, n = 12) were measured in 13 subjects during multiple 30° head-up tilts during whole body heating. At the end of the heat stress, mean body temperature (36.8 ± 0.1 to 38.0 ± 0.1 °C) and sweat rate at all sites were significantly elevated. No significant correlations were observed between mean body temperature and the change in SSNA during head-up tilt (r = 0.07; P = 0.62), sweating within the innervated area (r = 0.06; P = 0.56), sweating at the neostigmine treated site (r = 0.04; P = 0.69), or sweating at the control site (r = 0.01; P = 0.94). Also, for each tilt throughout the heat stress, there were no significant differences in sweat rate (final tilt sweat rates were 0.69 ± 0.11 and 0.68 ± 0.11 mg · cm-2 · min-1 within the innervated area; 1.04 ± 0.16 and 1.06 ± 0.16 mg · cm-2 · min-1 at the neostigmine-treated site; and 0.85 ± 0.15 and 0.85 ± 0.15 mg · cm-2 · min-1 at the control site, for supine and tilf, respectively). Hence, these data indicate that mean body temperature does not modulate eccrine sweat rate during baroreceptor unloading induced via 30° head-up tilt.",
keywords = "Baroreceptor unloading, Microneurography, Whole body heating",
author = "Wilson, {Thad E.} and Jian Cui and Crandall, {Craig G.}",
year = "2005",
month = "4",
doi = "10.1152/japplphysiol.00648.2004",
language = "English (US)",
volume = "98",
pages = "1207--1212",
journal = "Journal of Applied Physiology",
issn = "0161-7567",
publisher = "American Physiological Society",
number = "4",

}

TY - JOUR

T1 - Mean body temperature does not modulate eccrine sweat rate during upright tilt

AU - Wilson, Thad E.

AU - Cui, Jian

AU - Crandall, Craig G.

PY - 2005/4

Y1 - 2005/4

N2 - Conflicting reports exist about the role of baroreflexes in efferent control of eccrine sweat rate. These conflicting reports may be due to differing mean body temperatures between studies. The purpose of this project was to test the hypothesis that mean body temperature modulates the effect of head-up tilt on sweat rate and skin sympathetic nerve activity (SSNA). To address this question, mean body temperature (0.9 · internal temperature + 0.1 · mean skin temperature), SSNA (microneurography of peroneal nerve, n = 8), and sweat rate (from an area innervated by the peroneal nerve and from two forearm sites, one perfused with neostigmine to augment sweating at lower mean body temperatures and the second with the vehicle, n = 12) were measured in 13 subjects during multiple 30° head-up tilts during whole body heating. At the end of the heat stress, mean body temperature (36.8 ± 0.1 to 38.0 ± 0.1 °C) and sweat rate at all sites were significantly elevated. No significant correlations were observed between mean body temperature and the change in SSNA during head-up tilt (r = 0.07; P = 0.62), sweating within the innervated area (r = 0.06; P = 0.56), sweating at the neostigmine treated site (r = 0.04; P = 0.69), or sweating at the control site (r = 0.01; P = 0.94). Also, for each tilt throughout the heat stress, there were no significant differences in sweat rate (final tilt sweat rates were 0.69 ± 0.11 and 0.68 ± 0.11 mg · cm-2 · min-1 within the innervated area; 1.04 ± 0.16 and 1.06 ± 0.16 mg · cm-2 · min-1 at the neostigmine-treated site; and 0.85 ± 0.15 and 0.85 ± 0.15 mg · cm-2 · min-1 at the control site, for supine and tilf, respectively). Hence, these data indicate that mean body temperature does not modulate eccrine sweat rate during baroreceptor unloading induced via 30° head-up tilt.

AB - Conflicting reports exist about the role of baroreflexes in efferent control of eccrine sweat rate. These conflicting reports may be due to differing mean body temperatures between studies. The purpose of this project was to test the hypothesis that mean body temperature modulates the effect of head-up tilt on sweat rate and skin sympathetic nerve activity (SSNA). To address this question, mean body temperature (0.9 · internal temperature + 0.1 · mean skin temperature), SSNA (microneurography of peroneal nerve, n = 8), and sweat rate (from an area innervated by the peroneal nerve and from two forearm sites, one perfused with neostigmine to augment sweating at lower mean body temperatures and the second with the vehicle, n = 12) were measured in 13 subjects during multiple 30° head-up tilts during whole body heating. At the end of the heat stress, mean body temperature (36.8 ± 0.1 to 38.0 ± 0.1 °C) and sweat rate at all sites were significantly elevated. No significant correlations were observed between mean body temperature and the change in SSNA during head-up tilt (r = 0.07; P = 0.62), sweating within the innervated area (r = 0.06; P = 0.56), sweating at the neostigmine treated site (r = 0.04; P = 0.69), or sweating at the control site (r = 0.01; P = 0.94). Also, for each tilt throughout the heat stress, there were no significant differences in sweat rate (final tilt sweat rates were 0.69 ± 0.11 and 0.68 ± 0.11 mg · cm-2 · min-1 within the innervated area; 1.04 ± 0.16 and 1.06 ± 0.16 mg · cm-2 · min-1 at the neostigmine-treated site; and 0.85 ± 0.15 and 0.85 ± 0.15 mg · cm-2 · min-1 at the control site, for supine and tilf, respectively). Hence, these data indicate that mean body temperature does not modulate eccrine sweat rate during baroreceptor unloading induced via 30° head-up tilt.

KW - Baroreceptor unloading

KW - Microneurography

KW - Whole body heating

UR - http://www.scopus.com/inward/record.url?scp=15444368104&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15444368104&partnerID=8YFLogxK

U2 - 10.1152/japplphysiol.00648.2004

DO - 10.1152/japplphysiol.00648.2004

M3 - Article

VL - 98

SP - 1207

EP - 1212

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 0161-7567

IS - 4

ER -