Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial

Peter G. McGovern, Sandra A. Carson, Huiman X. Barnhart, Evan R. Myers, Richard S. Legro, Michael P. Diamond, Bruce R. Carr, William D. Schlaff, Christos Coutifaris, Nicholas A. Cataldo, Michael P. Steinkampf, John E. Nestler, Gabey Gosman, Phyllis C. Leppert, Linda C. Giudice

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We investigated whether poor adherence with metformin tablets may have contributed to the poor success rates seen in the metformin-containing arms of the Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial. Median adherence for both metformin and clomiphene citrate tablets was within acceptable limits and unrelated to ovulation: thus, failure to comply with physician recommendations for metformin dosing was not the reason for low ovulation and pregnancy rates in the PPCOS Trial.

Original languageEnglish (US)
Pages (from-to)1283-1286
Number of pages4
JournalFertility and sterility
Volume90
Issue number4
DOIs
StatePublished - Oct 1 2008

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial'. Together they form a unique fingerprint.

  • Cite this

    McGovern, P. G., Carson, S. A., Barnhart, H. X., Myers, E. R., Legro, R. S., Diamond, M. P., Carr, B. R., Schlaff, W. D., Coutifaris, C., Cataldo, N. A., Steinkampf, M. P., Nestler, J. E., Gosman, G., Leppert, P. C., & Giudice, L. C. (2008). Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial. Fertility and sterility, 90(4), 1283-1286. https://doi.org/10.1016/j.fertnstert.2007.09.004