Abstract
We investigated whether poor adherence with metformin tablets may have contributed to the poor success rates seen in the metformin-containing arms of the Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial. Median adherence for both metformin and clomiphene citrate tablets was within acceptable limits and unrelated to ovulation: thus, failure to comply with physician recommendations for metformin dosing was not the reason for low ovulation and pregnancy rates in the PPCOS Trial.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1283-1286 |
| Number of pages | 4 |
| Journal | Fertility and Sterility |
| Volume | 90 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 2008 |
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ASJC Scopus subject areas
- Obstetrics and Gynecology
- Reproductive Medicine
Cite this
Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial. / McGovern, Peter G.; Carson, Sandra A.; Barnhart, Huiman X.; Myers, Evan R.; Legro, Richard S.; Diamond, Michael P.; Carr, Bruce R.; Schlaff, William D.; Coutifaris, Christos; Cataldo, Nicholas A.; Steinkampf, Michael P.; Nestler, John E.; Gosman, Gabey; Leppert, Phyllis C.; Giudice, Linda C.
In: Fertility and Sterility, Vol. 90, No. 4, 10.2008, p. 1283-1286.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial
AU - McGovern, Peter G.
AU - Carson, Sandra A.
AU - Barnhart, Huiman X.
AU - Myers, Evan R.
AU - Legro, Richard S.
AU - Diamond, Michael P.
AU - Carr, Bruce R.
AU - Schlaff, William D.
AU - Coutifaris, Christos
AU - Cataldo, Nicholas A.
AU - Steinkampf, Michael P.
AU - Nestler, John E.
AU - Gosman, Gabey
AU - Leppert, Phyllis C.
AU - Giudice, Linda C.
PY - 2008/10
Y1 - 2008/10
N2 - We investigated whether poor adherence with metformin tablets may have contributed to the poor success rates seen in the metformin-containing arms of the Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial. Median adherence for both metformin and clomiphene citrate tablets was within acceptable limits and unrelated to ovulation: thus, failure to comply with physician recommendations for metformin dosing was not the reason for low ovulation and pregnancy rates in the PPCOS Trial.
AB - We investigated whether poor adherence with metformin tablets may have contributed to the poor success rates seen in the metformin-containing arms of the Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial. Median adherence for both metformin and clomiphene citrate tablets was within acceptable limits and unrelated to ovulation: thus, failure to comply with physician recommendations for metformin dosing was not the reason for low ovulation and pregnancy rates in the PPCOS Trial.
UR - http://www.scopus.com/inward/record.url?scp=52949098798&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=52949098798&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2007.09.004
DO - 10.1016/j.fertnstert.2007.09.004
M3 - Article
C2 - 18082737
AN - SCOPUS:52949098798
VL - 90
SP - 1283
EP - 1286
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 4
ER -