Medullary nuclear dysplasia (möbius syndrome) in an infant with recurrent apnea and jsoelectric eeg

Susan T. Iannaccone, Kevin E. Bove, Harold Fogelson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

From birth, an infant girl had repeated episodes of loss of consciousness, apnea and bradycardia, aphonia, and severe pharyngeal-esophageal discoordination. These functional deficits correlated with a gross and microscopic malformation of the medulla oblongata, which is characterized by profound deficits of motor and sensory nuclei and of the reticular formation. We have classified this as an example of Mobius syndrome. No etiology was suggested from the history. Histopathologic findings are compatible with an early massive insult to developing structures in the tegmentum of the medulla oblongata..

Original languageEnglish (US)
Pages (from-to)145-158
Number of pages14
JournalFetal and Pediatric Pathology
Volume1
Issue number2
DOIs
StatePublished - 1983

Fingerprint

Medulla Oblongata
Apnea
Aphonia
Mobius Syndrome
Reticular Formation
Unconsciousness
Bradycardia
History
Parturition

Keywords

  • Apnea
  • Electroencephalogram
  • Medullary nuclear dysplasia
  • Möbius syndrome

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Pediatrics, Perinatology, and Child Health

Cite this

Medullary nuclear dysplasia (möbius syndrome) in an infant with recurrent apnea and jsoelectric eeg. / Iannaccone, Susan T.; Bove, Kevin E.; Fogelson, Harold.

In: Fetal and Pediatric Pathology, Vol. 1, No. 2, 1983, p. 145-158.

Research output: Contribution to journalArticle

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