Membranous nephropathy: A ten-year journey of discoveries

Research output: Contribution to journalReview article

Abstract

Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Over the last decade important research discoveries have revealed that most “idiopathic” cases are caused by autoantibodies to podocyte antigens including phospholipase A2 receptor (PLA2R) and thrombospondin type 1 domain containing 7A (THSD7A). In this review, we will discuss the histopathology of primary MN, recent revelations regarding pathogenesis, and ancillary tests.

Original languageEnglish (US)
Pages (from-to)116-120
Number of pages5
JournalSeminars in Diagnostic Pathology
Volume37
Issue number3
DOIs
StatePublished - May 2020

Keywords

  • Membranous nephropathy
  • PLA2R
  • THSD7A

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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