Men and women from the STRIDE clinical trial: An assessment of stimulant abstinence symptom severity at residential treatment entry

Karen G. Chartier, Katherine Sanchez, Therese K. Killeen, Allison Burrow, Thomas Carmody, Tracy L. Greer, Madhukar H. Trivedi

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Background and Objectives: Gender-specific factors associated with stimulant abstinence severity were examined in a stimulant abusing or dependent residential treatment sample (N=302). Method Bivariate statistics tested gender differences in stimulant abstinence symptoms, measured by participant-reported experiences of early withdrawal. Multivariate linear regression examined gender and other predictors of stimulant abstinence symptom severity. Results: Women compared to men reported greater stimulant abstinence symptom severity. Anxiety disorders and individual anxiety-related abstinence symptoms accounted for this difference. African American race/ethnicity was predictive of lower stimulant abstinence severity. Discussion and Conclusions Women were more sensitive to anxiety-related stimulant withdrawal symptoms. Scientific Significance Clinics that address anxiety-related abstinence symptoms, which more commonly occur in women, may improve treatment outcome. (Am J Addict 2015;XX:XX-XX)

Original languageEnglish (US)
Pages (from-to)336-340
Number of pages5
JournalAmerican Journal on Addictions
Volume24
Issue number4
DOIs
StatePublished - Jun 1 2015

Keywords

  • Anxiety
  • Early withdrawal symptoms
  • Gender
  • Stimulant abstinence severity

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Clinical Psychology
  • Psychiatry and Mental health

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