Met-enkephalin levels in midbrain dopamine regions of inbred mouse strains which differ in the number of dopamine neurons

M. K. Sanghera; I. Fuchs; E. Weidmer-Mikhail; S. G. Speciale

doi:10.1016/0006-8993(87)91462-4

Met-enkephalin levels in midbrain dopamine regions of inbred mouse strains which differ in the number of dopamine neurons

M. K. Sanghera, I. Fuchs, E. Weidmer-Mikhail, S. G. Speciale

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6 Scopus citations

Abstract

The Met-enkephalin content in tissue micropunches of the substantia nigra zona compacta, ventral tegmental area and the caudate nucleus in BALB/c and CBA mouse strains was measured by radioimmunoassay. The CBA strain had significantly higher Met-enkephalin levels in all 3 regions than the BALB/c strain. These differences should be taken into account when relating the intensity of dopamine-induced behaviors to the number of dopamine neurons.

Original language	English (US)
Pages (from-to)	200-203
Number of pages	4
Journal	Brain Research
Volume	412
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(87)91462-4
State	Published - May 26 1987

Keywords

BALB/c mouse strain
CBA mouse strain
Caudate
Met-Enkephalin
Micropunch
Radioimmunoassay
Substantia nigra zona compacta
Ventral tegmental area

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(87)91462-4

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title = "Met-enkephalin levels in midbrain dopamine regions of inbred mouse strains which differ in the number of dopamine neurons",

abstract = "The Met-enkephalin content in tissue micropunches of the substantia nigra zona compacta, ventral tegmental area and the caudate nucleus in BALB/c and CBA mouse strains was measured by radioimmunoassay. The CBA strain had significantly higher Met-enkephalin levels in all 3 regions than the BALB/c strain. These differences should be taken into account when relating the intensity of dopamine-induced behaviors to the number of dopamine neurons.",

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AU - Sanghera, M. K.

AU - Fuchs, I.

AU - Weidmer-Mikhail, E.

AU - Speciale, S. G.

PY - 1987/5/26

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AB - The Met-enkephalin content in tissue micropunches of the substantia nigra zona compacta, ventral tegmental area and the caudate nucleus in BALB/c and CBA mouse strains was measured by radioimmunoassay. The CBA strain had significantly higher Met-enkephalin levels in all 3 regions than the BALB/c strain. These differences should be taken into account when relating the intensity of dopamine-induced behaviors to the number of dopamine neurons.

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KW - CBA mouse strain

KW - Caudate

KW - Met-Enkephalin

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KW - Radioimmunoassay

KW - Substantia nigra zona compacta

KW - Ventral tegmental area

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Met-enkephalin levels in midbrain dopamine regions of inbred mouse strains which differ in the number of dopamine neurons

Abstract

Keywords

ASJC Scopus subject areas

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