Met-enkephalin levels in midbrain dopamine regions of inbred mouse strains which differ in the number of dopamine neurons

M. K. Sanghera, I. Fuchs, E. Weidmer-Mikhail, S. G. Speciale

Research output: Contribution to journalArticle

6 Scopus citations


The Met-enkephalin content in tissue micropunches of the substantia nigra zona compacta, ventral tegmental area and the caudate nucleus in BALB/c and CBA mouse strains was measured by radioimmunoassay. The CBA strain had significantly higher Met-enkephalin levels in all 3 regions than the BALB/c strain. These differences should be taken into account when relating the intensity of dopamine-induced behaviors to the number of dopamine neurons.

Original languageEnglish (US)
Pages (from-to)200-203
Number of pages4
JournalBrain Research
Issue number1
StatePublished - May 26 1987



  • BALB/c mouse strain
  • CBA mouse strain
  • Caudate
  • Met-Enkephalin
  • Micropunch
  • Radioimmunoassay
  • Substantia nigra zona compacta
  • Ventral tegmental area

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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