Metabolic Adaptation Fuels Lymph Node Metastasis

Jessalyn M. Ubellacker; Sean J. Morrison

doi:10.1016/j.cmet.2019.03.006

Metabolic Adaptation Fuels Lymph Node Metastasis

Jessalyn M. Ubellacker, Sean J. Morrison

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Many cancers metastasize regionally through lymphatics before metastasizing systemically through blood vessels. However, metastasis through blood has been studied much more extensively than metastasis through lymph. Recently in Science, Lee et al. (2019) offered new insight into lymph node metastasis by showing that melanoma cells must undergo metabolic changes during this process and that it is driven by localized accumulation of bile acids.

Original language	English (US)
Pages (from-to)	785-786
Number of pages	2
Journal	Cell Metabolism
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2019.03.006
State	Published - Apr 2 2019

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

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10.1016/j.cmet.2019.03.006

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title = "Metabolic Adaptation Fuels Lymph Node Metastasis",

abstract = "Many cancers metastasize regionally through lymphatics before metastasizing systemically through blood vessels. However, metastasis through blood has been studied much more extensively than metastasis through lymph. Recently in Science, Lee et al. (2019) offered new insight into lymph node metastasis by showing that melanoma cells must undergo metabolic changes during this process and that it is driven by localized accumulation of bile acids.",

author = "Ubellacker, {Jessalyn M.} and Morrison, {Sean J.}",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = apr,

day = "2",

doi = "10.1016/j.cmet.2019.03.006",

language = "English (US)",

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T1 - Metabolic Adaptation Fuels Lymph Node Metastasis

AU - Ubellacker, Jessalyn M.

AU - Morrison, Sean J.

PY - 2019/4/2

Y1 - 2019/4/2

N2 - Many cancers metastasize regionally through lymphatics before metastasizing systemically through blood vessels. However, metastasis through blood has been studied much more extensively than metastasis through lymph. Recently in Science, Lee et al. (2019) offered new insight into lymph node metastasis by showing that melanoma cells must undergo metabolic changes during this process and that it is driven by localized accumulation of bile acids.

AB - Many cancers metastasize regionally through lymphatics before metastasizing systemically through blood vessels. However, metastasis through blood has been studied much more extensively than metastasis through lymph. Recently in Science, Lee et al. (2019) offered new insight into lymph node metastasis by showing that melanoma cells must undergo metabolic changes during this process and that it is driven by localized accumulation of bile acids.

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U2 - 10.1016/j.cmet.2019.03.006

DO - 10.1016/j.cmet.2019.03.006

M3 - Short survey

C2 - 30943388

AN - SCOPUS:85062808153

SN - 1550-4131

VL - 29

SP - 785

EP - 786

JO - Cell Metabolism

JF - Cell Metabolism

IS - 4

ER -

Metabolic Adaptation Fuels Lymph Node Metastasis

Abstract

ASJC Scopus subject areas

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