Metabolic Adaptation Fuels Lymph Node Metastasis

Jessalyn M. Ubellacker, Sean J Morrison

Research output: Contribution to journalShort survey

1 Scopus citations

Abstract

Many cancers metastasize regionally through lymphatics before metastasizing systemically through blood vessels. However, metastasis through blood has been studied much more extensively than metastasis through lymph. Recently in Science, Lee et al. (2019) offered new insight into lymph node metastasis by showing that melanoma cells must undergo metabolic changes during this process and that it is driven by localized accumulation of bile acids.

Original languageEnglish (US)
Pages (from-to)785-786
Number of pages2
JournalCell Metabolism
Volume29
Issue number4
DOIs
StatePublished - Apr 2 2019

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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