Metabolic exit from naive pluripotency

Jun Wu, Juan Carlos Izpisua Belmonte

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Spatiotemporally distinct pluripotent states captured in vitro provide an accessible way of modelling early human development. An intricate interplay between the metabolome and histone modifications is now shown to drive the metabolic switch from human naive to primed pluripotency, one of the earliest steps of embryogenesis.

Original languageEnglish (US)
Pages (from-to)1519-1521
Number of pages3
JournalNature Cell Biology
Volume17
Issue number12
DOIs
StatePublished - Nov 27 2015
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology

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