Metabolic syndrome update

Research output: Contribution to journalArticle

159 Citations (Scopus)

Abstract

The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.

Original languageEnglish (US)
JournalTrends in Cardiovascular Medicine
DOIs
StateAccepted/In press - 2015

Fingerprint

Bariatric Surgery
Dyslipidemias
Energy Intake
Type 2 Diabetes Mellitus
Insulin Resistance
Life Style
Cardiovascular Diseases
Obesity
Blood Pressure
Glucose
Drug Therapy

Keywords

  • Diabetes
  • Dyslipidemia
  • Hypertension
  • Metabolic syndrome
  • Nutrition
  • Obesity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Metabolic syndrome update. / Grundy, Scott M.

In: Trends in Cardiovascular Medicine, 2015.

Research output: Contribution to journalArticle

@article{aac7a43a7f1a48e2b5923c4d0a704fcc,
title = "Metabolic syndrome update",
abstract = "The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.",
keywords = "Diabetes, Dyslipidemia, Hypertension, Metabolic syndrome, Nutrition, Obesity",
author = "Grundy, {Scott M}",
year = "2015",
doi = "10.1016/j.tcm.2015.10.004",
language = "English (US)",
journal = "Trends in Cardiovascular Medicine",
issn = "1050-1738",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Metabolic syndrome update

AU - Grundy, Scott M

PY - 2015

Y1 - 2015

N2 - The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.

AB - The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.

KW - Diabetes

KW - Dyslipidemia

KW - Hypertension

KW - Metabolic syndrome

KW - Nutrition

KW - Obesity

UR - http://www.scopus.com/inward/record.url?scp=84949257250&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84949257250&partnerID=8YFLogxK

U2 - 10.1016/j.tcm.2015.10.004

DO - 10.1016/j.tcm.2015.10.004

M3 - Article

C2 - 26654259

AN - SCOPUS:84949257250

JO - Trends in Cardiovascular Medicine

JF - Trends in Cardiovascular Medicine

SN - 1050-1738

ER -