Metabolism of [3-13c]-pyruvate by cysticerci of taenia crassiceps

I. Corbin, R. Simcoff, M. Novak, B. J. Blackburn

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Carbon-13 decoupled 1H spin-echo nuclear magnetic resonance (NMR) spectra, with and without 13C population inversion, of extracts of Taenia crassiceps cysticerci incubated in media containing [3-13C]-pyruvate showed 13C enrichment in alanine, lactate, acetate, succinate, and citrate. Labeling in the latter three metabolites provides substantial evidence that the malic enzyme reaction in this cestode also functions in the direction opposite to that in which it is normally portrayed. The direct passage of pyruvate from the cytosol to the mitochondrion is suggested by the greater percentage of 13C detected in acetate relative to succinate.

Original languageEnglish (US)
Pages (from-to)516-518
Number of pages3
JournalParasitology Research
Issue number6
StatePublished - 1998

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)
  • Insect Science
  • Infectious Diseases


Dive into the research topics of 'Metabolism of [3-13c]-pyruvate by cysticerci of taenia crassiceps'. Together they form a unique fingerprint.

Cite this