TY - JOUR
T1 - Methods in Mammalian Autophagy Research
AU - Mizushima, Noboru
AU - Yoshimori, Tamotsu
AU - Levine, Beth
N1 - Funding Information:
We thank Akiko Kuma, Eisuke Itakura, and Chieko Kishi for providing the data used in this manuscript. This work was supported by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan (N.M. and T.Y.), the Toray Science Foundation (N.M.), the Takeda Science Foundation (N.M. and T.Y.), and National Institutes of Health grants RO1 CA85254, RO1 CA109618, and U54 AI057156 (B.L.).
PY - 2010/2/5
Y1 - 2010/2/5
N2 - Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.
AB - Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.
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U2 - 10.1016/j.cell.2010.01.028
DO - 10.1016/j.cell.2010.01.028
M3 - Short survey
C2 - 20144757
AN - SCOPUS:75749122303
SN - 0092-8674
VL - 140
SP - 313
EP - 326
JO - Cell
JF - Cell
IS - 3
ER -