Methods in Mammalian Autophagy Research

Noboru Mizushima, Tamotsu Yoshimori, Beth Levine

Research output: Contribution to journalArticle

2489 Citations (Scopus)

Abstract

Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.

Original languageEnglish (US)
Pages (from-to)313-326
Number of pages14
JournalCell
Volume140
Issue number3
DOIs
StatePublished - Feb 5 2010

Fingerprint

Autophagy
Research
Physiological Phenomena
Pathologic Processes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Methods in Mammalian Autophagy Research. / Mizushima, Noboru; Yoshimori, Tamotsu; Levine, Beth.

In: Cell, Vol. 140, No. 3, 05.02.2010, p. 313-326.

Research output: Contribution to journalArticle

Mizushima, N, Yoshimori, T & Levine, B 2010, 'Methods in Mammalian Autophagy Research', Cell, vol. 140, no. 3, pp. 313-326. https://doi.org/10.1016/j.cell.2010.01.028
Mizushima, Noboru ; Yoshimori, Tamotsu ; Levine, Beth. / Methods in Mammalian Autophagy Research. In: Cell. 2010 ; Vol. 140, No. 3. pp. 313-326.
@article{9386b3768e494505a8e5d2b698213a5a,
title = "Methods in Mammalian Autophagy Research",
abstract = "Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.",
author = "Noboru Mizushima and Tamotsu Yoshimori and Beth Levine",
year = "2010",
month = "2",
day = "5",
doi = "10.1016/j.cell.2010.01.028",
language = "English (US)",
volume = "140",
pages = "313--326",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "3",

}

TY - JOUR

T1 - Methods in Mammalian Autophagy Research

AU - Mizushima, Noboru

AU - Yoshimori, Tamotsu

AU - Levine, Beth

PY - 2010/2/5

Y1 - 2010/2/5

N2 - Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.

AB - Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.

UR - http://www.scopus.com/inward/record.url?scp=75749122303&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=75749122303&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2010.01.028

DO - 10.1016/j.cell.2010.01.028

M3 - Article

VL - 140

SP - 313

EP - 326

JO - Cell

JF - Cell

SN - 0092-8674

IS - 3

ER -