Methods in Mammalian Autophagy Research

Noboru Mizushima, Tamotsu Yoshimori, Beth Levine

Research output: Contribution to journalShort survey

2883 Scopus citations

Abstract

Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.

Original languageEnglish (US)
Pages (from-to)313-326
Number of pages14
JournalCell
Volume140
Issue number3
DOIs
StatePublished - Feb 5 2010

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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