Abstract
Dehydrative alkylation of alcohols with methyl phenylsulfonylacetate under modified Mitsunobu conditions followed by desulfonylation using magnesium affords two-carbon elongated methyl carboxylates in good to excellent yields. Diols and bromoalcohols furnish cycloalkylcarboxylates.
Original language | English (US) |
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Pages (from-to) | 1127-1128 |
Number of pages | 2 |
Journal | Synlett |
Volume | 1995 |
Issue number | 11 |
DOIs | |
State | Published - Nov 1995 |
Keywords
- C-C bond formation
- Mitsunobu
- carboxylation
- desulfonylation
ASJC Scopus subject areas
- Organic Chemistry