Methyl Carboxymethylenation of Alcohols via Dehydrative Alkylation

Jurong Yu, Jing Yu Lai, J R Falck

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Dehydrative alkylation of alcohols with methyl phenylsulfonylacetate under modified Mitsunobu conditions followed by desulfonylation using magnesium affords two-carbon elongated methyl carboxylates in good to excellent yields. Diols and bromoalcohols furnish cycloalkylcarboxylates.

Original languageEnglish (US)
Pages (from-to)1127-1128
Number of pages2
JournalSynlett
Volume1995
Issue number11
DOIs
StatePublished - Nov 1 1995

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Alkylation
Magnesium
Carbon
Alcohols

Keywords

  • C-C bond formation
  • carboxylation
  • desulfonylation
  • Mitsunobu

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Methyl Carboxymethylenation of Alcohols via Dehydrative Alkylation. / Yu, Jurong; Lai, Jing Yu; Falck, J R.

In: Synlett, Vol. 1995, No. 11, 01.11.1995, p. 1127-1128.

Research output: Contribution to journalArticle

Yu, Jurong ; Lai, Jing Yu ; Falck, J R. / Methyl Carboxymethylenation of Alcohols via Dehydrative Alkylation. In: Synlett. 1995 ; Vol. 1995, No. 11. pp. 1127-1128.
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