TY - JOUR
T1 - Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia
AU - Ríos, Ana María
AU - Fonseca-Aten, Mónica
AU - Mejías, Asunción
AU - Chávez-Bueno, Susana
AU - Katz, Kathy
AU - Gómez, Ana María
AU - McCracken, George H.
AU - Ramilo, Octavio
AU - Hardy, R. Doug
PY - 2005/9
Y1 - 2005/9
N2 - We evaluated the efficacy of azithromycin therapy given as a single high dose or divided over 5 days for the treatment of mild experimental Mycoplasma pneumoniae pneumonia. Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens.
AB - We evaluated the efficacy of azithromycin therapy given as a single high dose or divided over 5 days for the treatment of mild experimental Mycoplasma pneumoniae pneumonia. Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens.
UR - http://www.scopus.com/inward/record.url?scp=24144436945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=24144436945&partnerID=8YFLogxK
U2 - 10.1128/AAC.49.9.3970-3973.2005
DO - 10.1128/AAC.49.9.3970-3973.2005
M3 - Article
C2 - 16127085
AN - SCOPUS:24144436945
SN - 0066-4804
VL - 49
SP - 3970
EP - 3973
JO - Antimicrobial agents and chemotherapy
JF - Antimicrobial agents and chemotherapy
IS - 9
ER -