Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice

Medicine & Life Sciences

• Probiotics 92%
• Bile Acids and Salts 89%
• Microbiota 85%
• Down-Regulation 60%
• Liver 44%
• Gastrointestinal Microbiome 15%
• Enterohepatic Circulation 11%
• Liver X Receptors 10%
• Fibroblast Growth Factor Receptors 10%
• Hepatobiliary Elimination 9%
• Fibroblast Growth Factors 9%
• Biotransformation 9%
• Hydrophobic and Hydrophilic Interactions 8%
• Health Status 6%
• Therapeutics 2%

Chemical Compounds

• Bile Acid 100%
• Modification 48%
• Growth Factor 18%
• Agonist 7%
• Hydrophobicity 6%
• Protective 6%
• Metabolic 6%
• Pharmacological Metabolism 6%