Microscopic polyangiitis presenting as idiopathic pulmonary fibrosis: Is anti-neutrophilic cytoplasmic antibody testing indicated?

Ishak A. Mansi, Adriana Opran, Damanpaul Sondhi, Raji Ayinla, Fred Rosner

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

We report a 55-year old woman with microscopic polyangiitis who presented with idiopathic pulmonary fibrosis and 1 year later developed hematuria and proteinuria. She had a high serum level of perinuclear anti-neutrophilic cytoplasmic antibodies. Renal angiogram was normal. The diagnosis of microscopic polyangiitis was confirmed by renal biopsy, which showed pauci-immune crescentic glomerulonephritis. The patient received immunosuppressive therapy and improved markedly. Consideration of small vessel vasculitis is important in the differential diagnosis of idiopathic pulmonary fibrosis.

Original languageEnglish (US)
Pages (from-to)201-202
Number of pages2
JournalAmerican Journal of the Medical Sciences
Volume321
Issue number3
DOIs
StatePublished - 2001

Keywords

  • Anti-neutrophilic cytoplasmic antibodies (ANCA)
  • Idiopathic pulmonary fibrosis
  • Microscopic polyangiitis

ASJC Scopus subject areas

  • Medicine(all)

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