TY - GEN
T1 - Microvascular anastomosis in rodent model evaluated by Fourier domain Doppler optical coherence tomography
AU - Huang, Yong
AU - Tong, Dedi
AU - Zhu, Shan
AU - Wu, Lehao
AU - Ibrahim, Zuhaib
AU - Lee, Wp Andrew
AU - Brandacher, Gerald
AU - Kang, Jin U.
PY - 2013
Y1 - 2013
N2 - Vascular and microvascular anastomosis are critical components of reconstructive microsurgery, vascular surgery and transplant surgery. Imaging modality that provides immediate, real-time in-depth view and 3D structure and flow information of the surgical site can be a great valuable tool for the surgeon to evaluate surgical outcome following both conventional and innovative anastomosis techniques, thus potentially increase the surgical success rate. Microvascular anastomosis for vessels with outer diameter smaller than 1.0 mm is extremely challenging and effective evaluation of the outcome is very difficult if not impossible using computed tomography (CT) angiograms, magnetic resonance (MR) angiograms and ultrasound Doppler. Optical coherence tomography (OCT) is a non-invasive high-resolution (micron level), high-speed, 3D imaging modality that has been adopted widely in biomedical and clinical applications. Phaseresolved Doppler OCT that explores the phase information of OCT signals has been shown to be capable of characterizing dynamic blood flow clinically. In this work, we explore the capability of Fourier domain Doppler OCT as an evaluation tool to detect commonly encountered post-operative complications that will cause surgical failure and to confirm positive result with surgeon’s observation. Both suture and cuff based techniques were evaluated on the femoral artery and vein in the rodent model.
AB - Vascular and microvascular anastomosis are critical components of reconstructive microsurgery, vascular surgery and transplant surgery. Imaging modality that provides immediate, real-time in-depth view and 3D structure and flow information of the surgical site can be a great valuable tool for the surgeon to evaluate surgical outcome following both conventional and innovative anastomosis techniques, thus potentially increase the surgical success rate. Microvascular anastomosis for vessels with outer diameter smaller than 1.0 mm is extremely challenging and effective evaluation of the outcome is very difficult if not impossible using computed tomography (CT) angiograms, magnetic resonance (MR) angiograms and ultrasound Doppler. Optical coherence tomography (OCT) is a non-invasive high-resolution (micron level), high-speed, 3D imaging modality that has been adopted widely in biomedical and clinical applications. Phaseresolved Doppler OCT that explores the phase information of OCT signals has been shown to be capable of characterizing dynamic blood flow clinically. In this work, we explore the capability of Fourier domain Doppler OCT as an evaluation tool to detect commonly encountered post-operative complications that will cause surgical failure and to confirm positive result with surgeon’s observation. Both suture and cuff based techniques were evaluated on the femoral artery and vein in the rodent model.
KW - Fourier domain Doppler optical coherence tomography
KW - Microvascular anastomosis
KW - Reconstructive surgery
UR - http://www.scopus.com/inward/record.url?scp=84896964256&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84896964256&partnerID=8YFLogxK
U2 - 10.1117/12.2041975
DO - 10.1117/12.2041975
M3 - Conference contribution
AN - SCOPUS:84896964256
SN - 9780819498472
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII
PB - SPIE
T2 - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII
Y2 - 3 February 2014 through 5 February 2014
ER -