Microvascular free tissue reconstruction in the patient with multiple courses of radiation

Eli A. Gordin, Yadranko Ducic

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objectives/Hypothesis: To assess the feasibility of microvascular free tissue transfer in the multiply irradiated patient. Study Design: Retrospective cohort analysis of 48 patients in a tertiary care, private practice setting. Methods: Inclusion criteria were defined as patients who received multiple courses of radiation and underwent subsequent free tissue reconstruction to manage treatment-related complications (n = 24) or defects following additional oncologic surgery (n = 24). The main outcome measures included total and partial flap necrosis, hardware exposure, and pharyngocutaneous fistula. The minimum follow-up was 6 months. Results: One case of total flap failure, two cases of partial skin paddle necrosis, one case of poor wound healing of the surrounding tissue to the flap, six cases of hardware exposure, 11 cases of fistula with eight requiring operative intervention, three cases requiring and additional free flap to supplement reconstruction, and one stroke. Conclusions: Microvascular free tissue transfer to the head and neck is expected to provide a successful reconstruction in patients who have received multiple courses of radiation and who develop second primary tumors, recurrence of disease, or who suffer from late complications of their radiation therapy.

Original languageEnglish (US)
Pages (from-to)2252-2256
Number of pages5
JournalLaryngoscope
Volume124
Issue number10
DOIs
StatePublished - Jan 1 2014

Fingerprint

Radiation
Fistula
Necrosis
Free Tissue Flaps
Private Practice
Tertiary Healthcare
Wound Healing
Cohort Studies
Neck
Radiotherapy
Retrospective Studies
Stroke
Head
Outcome Assessment (Health Care)
Recurrence
Skin
Neoplasms
Therapeutics

Keywords

  • Complications of radiation therapy
  • Microvascular free tissue transfer
  • Pharyngocutaneous fistula
  • Radionecrosis

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Microvascular free tissue reconstruction in the patient with multiple courses of radiation. / Gordin, Eli A.; Ducic, Yadranko.

In: Laryngoscope, Vol. 124, No. 10, 01.01.2014, p. 2252-2256.

Research output: Contribution to journalArticle

@article{f218322f0b094424ae14b1f5d62b6db5,
title = "Microvascular free tissue reconstruction in the patient with multiple courses of radiation",
abstract = "Objectives/Hypothesis: To assess the feasibility of microvascular free tissue transfer in the multiply irradiated patient. Study Design: Retrospective cohort analysis of 48 patients in a tertiary care, private practice setting. Methods: Inclusion criteria were defined as patients who received multiple courses of radiation and underwent subsequent free tissue reconstruction to manage treatment-related complications (n = 24) or defects following additional oncologic surgery (n = 24). The main outcome measures included total and partial flap necrosis, hardware exposure, and pharyngocutaneous fistula. The minimum follow-up was 6 months. Results: One case of total flap failure, two cases of partial skin paddle necrosis, one case of poor wound healing of the surrounding tissue to the flap, six cases of hardware exposure, 11 cases of fistula with eight requiring operative intervention, three cases requiring and additional free flap to supplement reconstruction, and one stroke. Conclusions: Microvascular free tissue transfer to the head and neck is expected to provide a successful reconstruction in patients who have received multiple courses of radiation and who develop second primary tumors, recurrence of disease, or who suffer from late complications of their radiation therapy.",
keywords = "Complications of radiation therapy, Microvascular free tissue transfer, Pharyngocutaneous fistula, Radionecrosis",
author = "Gordin, {Eli A.} and Yadranko Ducic",
year = "2014",
month = "1",
day = "1",
doi = "10.1002/lary.24681",
language = "English (US)",
volume = "124",
pages = "2252--2256",
journal = "Laryngoscope",
issn = "0023-852X",
publisher = "John Wiley and Sons Inc.",
number = "10",

}

TY - JOUR

T1 - Microvascular free tissue reconstruction in the patient with multiple courses of radiation

AU - Gordin, Eli A.

AU - Ducic, Yadranko

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Objectives/Hypothesis: To assess the feasibility of microvascular free tissue transfer in the multiply irradiated patient. Study Design: Retrospective cohort analysis of 48 patients in a tertiary care, private practice setting. Methods: Inclusion criteria were defined as patients who received multiple courses of radiation and underwent subsequent free tissue reconstruction to manage treatment-related complications (n = 24) or defects following additional oncologic surgery (n = 24). The main outcome measures included total and partial flap necrosis, hardware exposure, and pharyngocutaneous fistula. The minimum follow-up was 6 months. Results: One case of total flap failure, two cases of partial skin paddle necrosis, one case of poor wound healing of the surrounding tissue to the flap, six cases of hardware exposure, 11 cases of fistula with eight requiring operative intervention, three cases requiring and additional free flap to supplement reconstruction, and one stroke. Conclusions: Microvascular free tissue transfer to the head and neck is expected to provide a successful reconstruction in patients who have received multiple courses of radiation and who develop second primary tumors, recurrence of disease, or who suffer from late complications of their radiation therapy.

AB - Objectives/Hypothesis: To assess the feasibility of microvascular free tissue transfer in the multiply irradiated patient. Study Design: Retrospective cohort analysis of 48 patients in a tertiary care, private practice setting. Methods: Inclusion criteria were defined as patients who received multiple courses of radiation and underwent subsequent free tissue reconstruction to manage treatment-related complications (n = 24) or defects following additional oncologic surgery (n = 24). The main outcome measures included total and partial flap necrosis, hardware exposure, and pharyngocutaneous fistula. The minimum follow-up was 6 months. Results: One case of total flap failure, two cases of partial skin paddle necrosis, one case of poor wound healing of the surrounding tissue to the flap, six cases of hardware exposure, 11 cases of fistula with eight requiring operative intervention, three cases requiring and additional free flap to supplement reconstruction, and one stroke. Conclusions: Microvascular free tissue transfer to the head and neck is expected to provide a successful reconstruction in patients who have received multiple courses of radiation and who develop second primary tumors, recurrence of disease, or who suffer from late complications of their radiation therapy.

KW - Complications of radiation therapy

KW - Microvascular free tissue transfer

KW - Pharyngocutaneous fistula

KW - Radionecrosis

UR - http://www.scopus.com/inward/record.url?scp=84907885569&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907885569&partnerID=8YFLogxK

U2 - 10.1002/lary.24681

DO - 10.1002/lary.24681

M3 - Article

C2 - 24648254

AN - SCOPUS:84907885569

VL - 124

SP - 2252

EP - 2256

JO - Laryngoscope

JF - Laryngoscope

SN - 0023-852X

IS - 10

ER -