Microwave-assisted solid-phase synthesis of peptoids

Hernando J. Olivos, Prasanna G. Alluri, M. Muralidhar Reddy, Derek Salony, Thomas Kodadek

Research output: Contribution to journalArticle

152 Scopus citations

Abstract

(formula presented) Microwave irradiation reduces the reaction time for the solid-phase synthesis of peptoids. Under these conditions, coupling of each residue requires only 1 min. The purity and yields of peptoids synthesized in this way are as good as or better than those achieved using standard methods.

Original languageEnglish (US)
Pages (from-to)4057-4058
Number of pages2
JournalOrganic Letters
Volume4
Issue number23
DOIs
StatePublished - Nov 14 2002

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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    Olivos, H. J., Alluri, P. G., Reddy, M. M., Salony, D., & Kodadek, T. (2002). Microwave-assisted solid-phase synthesis of peptoids. Organic Letters, 4(23), 4057-4058. https://doi.org/10.1021/ol0267578