Migraine with and without aura and risk for cardiovascular disease

Bert B. Vargas, David W. Dodick, Dean M. Wingerchuk, Bart M. Demaerschalk

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Migraine, cardiovascular disease, and stroke are three highly prevalent and disabling conditions that exert a significant socioeconomic impact. The association between migraine and a twofold risk of stroke and myocardial infarction has been the topic of much debate. The mechanism underlying this link is largely unknown but may be the result of an increased prevalence of other conditions such as vasculopathies, hypercoagulable states, and patent foramen ovale seen in migraine with aura. Although many prior studies have demonstrated increased risks in women with migraine with aura, an emerging body of evidence is showing similar risks in men. These risks are further compounded with increased migraine frequency, smoking, and the use of oral contraceptive pills. Because the overall risk for stroke and myocardial infarction in migraineurs remains relatively low, recommendations at this time are limited to the modification of cardiovascular risk factors, such as smoking cessation and the avoidance of oral contraceptive pills, especially in women suffering from migraine with aura.

Original languageEnglish (US)
Pages (from-to)427-433
Number of pages7
JournalCurrent Atherosclerosis Reports
Volume10
Issue number5
DOIs
StatePublished - Dec 1 2008

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Migraine without Aura
Migraine with Aura
Cardiovascular Diseases
Migraine Disorders
Myocardial Infarction
Oral Contraceptives
Stroke
Patent Foramen Ovale
Smoking Cessation
Smoking

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Migraine with and without aura and risk for cardiovascular disease. / Vargas, Bert B.; Dodick, David W.; Wingerchuk, Dean M.; Demaerschalk, Bart M.

In: Current Atherosclerosis Reports, Vol. 10, No. 5, 01.12.2008, p. 427-433.

Research output: Contribution to journalReview article

Vargas, Bert B. ; Dodick, David W. ; Wingerchuk, Dean M. ; Demaerschalk, Bart M. / Migraine with and without aura and risk for cardiovascular disease. In: Current Atherosclerosis Reports. 2008 ; Vol. 10, No. 5. pp. 427-433.
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