Mineral metabolic effects of thyroidectomy and long-term outcomes in a family with MEN 2A.

H. G. Bone, L. J. Deftos, W. H. Snyder, C. Y. Pak

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We have followed a family with multiple endocrine neoplasia type 2A for 18 years. Four members have undergone total thyroidectomy for medullary thyroid carcinoma or C-cell hyperplasia, and one has required bilateral adrenalectomy for pheochromocytoma. None has developed hypercalcemic hyperparathyroidism, although parathyroid hormone levels were relatively high prethyroidectomy and fell postoperatively in the patients with high calcitonin levels. In three of the four cases, intestinal calcium absorption decreased following thyroidectomy.

Original languageEnglish (US)
Pages (from-to)258-260
Number of pages3
JournalHenry Ford Hospital Medical Journal
Volume40
Issue number3-4
StatePublished - 1992

Fingerprint

Multiple Endocrine Neoplasia Type 2a
Thyroidectomy
Minerals
Hyperparathyroidism
Adrenalectomy
Intestinal Absorption
Calcitonin
Pheochromocytoma
Parathyroid Hormone
Hyperplasia
Calcium
Medullary Thyroid cancer

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mineral metabolic effects of thyroidectomy and long-term outcomes in a family with MEN 2A. / Bone, H. G.; Deftos, L. J.; Snyder, W. H.; Pak, C. Y.

In: Henry Ford Hospital Medical Journal, Vol. 40, No. 3-4, 1992, p. 258-260.

Research output: Contribution to journalArticle

@article{090f9453540c4cb09e355506f85bd723,
title = "Mineral metabolic effects of thyroidectomy and long-term outcomes in a family with MEN 2A.",
abstract = "We have followed a family with multiple endocrine neoplasia type 2A for 18 years. Four members have undergone total thyroidectomy for medullary thyroid carcinoma or C-cell hyperplasia, and one has required bilateral adrenalectomy for pheochromocytoma. None has developed hypercalcemic hyperparathyroidism, although parathyroid hormone levels were relatively high prethyroidectomy and fell postoperatively in the patients with high calcitonin levels. In three of the four cases, intestinal calcium absorption decreased following thyroidectomy.",
author = "Bone, {H. G.} and Deftos, {L. J.} and Snyder, {W. H.} and Pak, {C. Y.}",
year = "1992",
language = "English (US)",
volume = "40",
pages = "258--260",
journal = "Henry Ford Hospital Medical Journal",
issn = "0018-0416",
publisher = "Henry Ford Hospital",
number = "3-4",

}

TY - JOUR

T1 - Mineral metabolic effects of thyroidectomy and long-term outcomes in a family with MEN 2A.

AU - Bone, H. G.

AU - Deftos, L. J.

AU - Snyder, W. H.

AU - Pak, C. Y.

PY - 1992

Y1 - 1992

N2 - We have followed a family with multiple endocrine neoplasia type 2A for 18 years. Four members have undergone total thyroidectomy for medullary thyroid carcinoma or C-cell hyperplasia, and one has required bilateral adrenalectomy for pheochromocytoma. None has developed hypercalcemic hyperparathyroidism, although parathyroid hormone levels were relatively high prethyroidectomy and fell postoperatively in the patients with high calcitonin levels. In three of the four cases, intestinal calcium absorption decreased following thyroidectomy.

AB - We have followed a family with multiple endocrine neoplasia type 2A for 18 years. Four members have undergone total thyroidectomy for medullary thyroid carcinoma or C-cell hyperplasia, and one has required bilateral adrenalectomy for pheochromocytoma. None has developed hypercalcemic hyperparathyroidism, although parathyroid hormone levels were relatively high prethyroidectomy and fell postoperatively in the patients with high calcitonin levels. In three of the four cases, intestinal calcium absorption decreased following thyroidectomy.

UR - http://www.scopus.com/inward/record.url?scp=0027015867&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027015867&partnerID=8YFLogxK

M3 - Article

VL - 40

SP - 258

EP - 260

JO - Henry Ford Hospital Medical Journal

JF - Henry Ford Hospital Medical Journal

SN - 0018-0416

IS - 3-4

ER -