Mirabegron: A new option in treating overactive bladder

Heidi Camus Turpen, Philippe E. Zimmern

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Antimuscarinic medications have long been the mainstay of drug treatment for overactive bladder. This article describes mirabegron, one of a new class of agents that relaxes the detrusor muscle directly via a beta3 adrenoceptor agonist. Mirabegron's efficacy on frequency, urgency, and urge incontinence was tested in several trials before its wide clinical introduction. However, caution is still needed as data are lacking on the drug's efficacy and safety in frail older adults and for long-term therapy.

Original languageEnglish (US)
Pages (from-to)16-18
Number of pages3
JournalJournal of the American Academy of Physician Assistants
Volume28
Issue number11
DOIs
StatePublished - 2015

Fingerprint

Overactive Urinary Bladder
Urge Urinary Incontinence
Frail Elderly
Muscarinic Antagonists
Pharmaceutical Preparations
Adrenergic Receptors
Safety
Muscles
Therapeutics
mirabegron

Keywords

  • Beta adrenoceptor agonist
  • Detrusor muscle
  • Incontinence
  • Mirabegron
  • Overactive bladder
  • Voiding frequency

ASJC Scopus subject areas

  • Nurse Assisting

Cite this

Mirabegron : A new option in treating overactive bladder. / Turpen, Heidi Camus; Zimmern, Philippe E.

In: Journal of the American Academy of Physician Assistants, Vol. 28, No. 11, 2015, p. 16-18.

Research output: Contribution to journalArticle

@article{c9e48de602bc4fe9a509cbcd21b7dc2c,
title = "Mirabegron: A new option in treating overactive bladder",
abstract = "Antimuscarinic medications have long been the mainstay of drug treatment for overactive bladder. This article describes mirabegron, one of a new class of agents that relaxes the detrusor muscle directly via a beta3 adrenoceptor agonist. Mirabegron's efficacy on frequency, urgency, and urge incontinence was tested in several trials before its wide clinical introduction. However, caution is still needed as data are lacking on the drug's efficacy and safety in frail older adults and for long-term therapy.",
keywords = "Beta adrenoceptor agonist, Detrusor muscle, Incontinence, Mirabegron, Overactive bladder, Voiding frequency",
author = "Turpen, {Heidi Camus} and Zimmern, {Philippe E.}",
year = "2015",
doi = "10.1097/01.JAA.0000472558.50124.7e",
language = "English (US)",
volume = "28",
pages = "16--18",
journal = "Journal of the American Academy of Physician Assistants",
issn = "1547-1896",
publisher = "American Academy of Physicians Assistants",
number = "11",

}

TY - JOUR

T1 - Mirabegron

T2 - A new option in treating overactive bladder

AU - Turpen, Heidi Camus

AU - Zimmern, Philippe E.

PY - 2015

Y1 - 2015

N2 - Antimuscarinic medications have long been the mainstay of drug treatment for overactive bladder. This article describes mirabegron, one of a new class of agents that relaxes the detrusor muscle directly via a beta3 adrenoceptor agonist. Mirabegron's efficacy on frequency, urgency, and urge incontinence was tested in several trials before its wide clinical introduction. However, caution is still needed as data are lacking on the drug's efficacy and safety in frail older adults and for long-term therapy.

AB - Antimuscarinic medications have long been the mainstay of drug treatment for overactive bladder. This article describes mirabegron, one of a new class of agents that relaxes the detrusor muscle directly via a beta3 adrenoceptor agonist. Mirabegron's efficacy on frequency, urgency, and urge incontinence was tested in several trials before its wide clinical introduction. However, caution is still needed as data are lacking on the drug's efficacy and safety in frail older adults and for long-term therapy.

KW - Beta adrenoceptor agonist

KW - Detrusor muscle

KW - Incontinence

KW - Mirabegron

KW - Overactive bladder

KW - Voiding frequency

UR - http://www.scopus.com/inward/record.url?scp=84945963488&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84945963488&partnerID=8YFLogxK

U2 - 10.1097/01.JAA.0000472558.50124.7e

DO - 10.1097/01.JAA.0000472558.50124.7e

M3 - Article

C2 - 26501573

AN - SCOPUS:84945963488

VL - 28

SP - 16

EP - 18

JO - Journal of the American Academy of Physician Assistants

JF - Journal of the American Academy of Physician Assistants

SN - 1547-1896

IS - 11

ER -