Mobile classification in microarray experiments

I. M. Dozmorov, M. Centola, N. Knowlton, Y. Tang

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

In a homogeneous group of samples, there are genes whose expression variations can be attributed to factors other than experimental errors. These factors can include natural biological oscillations or metabolic processes. These genes are rarely classified as 'interesting' based on their variability profile. However, their dynamic behaviour can tease out important clues about naturally occurring biological processes in the organism under study and can be used for group classification. Dynamical discriminate function analysis was developed on the concept that stable classification parameters (roots) can be derived from highly variable gene-expression data. Stability of these combinations implies a strongly compensatory relationship that may divulge functional interconnections.

Original languageEnglish (US)
Pages (from-to)84-91
Number of pages8
JournalScandinavian Journal of Immunology, Supplement
Volume62
Issue number1
DOIs
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Immunology

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