TY - GEN
T1 - Model based reconstruction for simultaneously imaging cerebral blood flow and de-oxygen hemoglobin distribution
AU - Miao, Peng
AU - Li, Nan
AU - Rege, Abhishek
AU - Tong, Shanbao
AU - Thakor, Nitish
PY - 2009
Y1 - 2009
N2 - Laser speckle imaging (LSI) and optical intrinsic signal (OIS) imaging are shown to produce high resolution information of cerebral blood flow(CBF) and de-oxygen hemoglobin(dHb) respectively. However, the cortex curvature and non-uniform illumination always result in the inhomogeneous impact and thus distort the CBF and dHb results. In this paper, we propose to extract both CBF and dHb images from raw speckle images. A parametric model for such inhomogeneity is estimated by adaptive window median-mean filtering and curve fitting technique to reconstruct the CBF and dHb image.
AB - Laser speckle imaging (LSI) and optical intrinsic signal (OIS) imaging are shown to produce high resolution information of cerebral blood flow(CBF) and de-oxygen hemoglobin(dHb) respectively. However, the cortex curvature and non-uniform illumination always result in the inhomogeneous impact and thus distort the CBF and dHb results. In this paper, we propose to extract both CBF and dHb images from raw speckle images. A parametric model for such inhomogeneity is estimated by adaptive window median-mean filtering and curve fitting technique to reconstruct the CBF and dHb image.
UR - http://www.scopus.com/inward/record.url?scp=84903857713&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903857713&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2009.5333603
DO - 10.1109/IEMBS.2009.5333603
M3 - Conference contribution
C2 - 19964288
AN - SCOPUS:84903857713
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 3236
EP - 3239
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Y2 - 2 September 2009 through 6 September 2009
ER -