Modeling axonal degeneration within the anterior visual system: Implications for demonstrating neuroprotection in multiple sclerosis

Elliot Frohman, Fiona Costello, Olaf Stuve, Peter Calabresi, David H. Miller, Simon J. Hickman, Robert Sergott, Amy Conger, Amber Salter, Kimberly A Hoggatt, Teresa C. Frohman, Laura Balcer, Robert Zivadinov

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

A major objective in multiple sclerosis therapeutics is to develop strategic targeting of specific injury pathways to provide neuroprotection and potentially even restoration. Here we underscore the potential utility of the anterior visual system for the purpose of modeling neuroprotection in response to novel therapies.

Original languageEnglish (US)
Pages (from-to)26-35
Number of pages10
JournalArchives of Neurology
Volume65
Issue number1
DOIs
StatePublished - Jan 2008

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Multiple Sclerosis
Wounds and Injuries
Therapeutics
Neuroprotection
Therapy
Pathway
Restoration
Degeneration
Modeling

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Modeling axonal degeneration within the anterior visual system : Implications for demonstrating neuroprotection in multiple sclerosis. / Frohman, Elliot; Costello, Fiona; Stuve, Olaf; Calabresi, Peter; Miller, David H.; Hickman, Simon J.; Sergott, Robert; Conger, Amy; Salter, Amber; Hoggatt, Kimberly A; Frohman, Teresa C.; Balcer, Laura; Zivadinov, Robert.

In: Archives of Neurology, Vol. 65, No. 1, 01.2008, p. 26-35.

Research output: Contribution to journalArticle

Frohman, E, Costello, F, Stuve, O, Calabresi, P, Miller, DH, Hickman, SJ, Sergott, R, Conger, A, Salter, A, Hoggatt, KA, Frohman, TC, Balcer, L & Zivadinov, R 2008, 'Modeling axonal degeneration within the anterior visual system: Implications for demonstrating neuroprotection in multiple sclerosis', Archives of Neurology, vol. 65, no. 1, pp. 26-35. https://doi.org/10.1001/archneurol.2007.10
Frohman, Elliot ; Costello, Fiona ; Stuve, Olaf ; Calabresi, Peter ; Miller, David H. ; Hickman, Simon J. ; Sergott, Robert ; Conger, Amy ; Salter, Amber ; Hoggatt, Kimberly A ; Frohman, Teresa C. ; Balcer, Laura ; Zivadinov, Robert. / Modeling axonal degeneration within the anterior visual system : Implications for demonstrating neuroprotection in multiple sclerosis. In: Archives of Neurology. 2008 ; Vol. 65, No. 1. pp. 26-35.
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