Molecular Imaging and Precision Medicine

PET/Computed Tomography and Therapy Response Assessment in Oncology

Sara Sheikhbahaei, Esther Mena, Puskar Pattanayak, Mehdi Taghipour, Lilja B. Solnes, Rathan M. Subramaniam

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

A variety of methods have been developed to assess tumor response to therapy. Standardized qualitative criteria based on 18F-fluoro-deoxyglucose PET/computed tomography have been proposed to evaluate the treatment effectiveness in specific cancers and these allow more accurate therapy response assessment and survival prognostication. Multiple studies have addressed the utility of the volumetric PET biomarkers as prognostic indicators but there is no consensus about the preferred segmentation methodology for these metrics. Heterogeneous intratumoral uptake was proposed as a novel PET metric for therapy response assessment. PET imaging techniques will be used to study the biological behavior of cancers during therapy.

Original languageEnglish (US)
Pages (from-to)105-118
Number of pages14
JournalPET Clinics
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2017

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Molecular Medicine
Precision Medicine
Molecular Imaging
medicine
therapy
tomography
Tomography
cancer
Neoplasms
biomarkers
Deoxyglucose
Therapeutics
imaging techniques
tumors
Biomarkers
methodology

Keywords

  • Molecular imaging
  • Oncology
  • PET/computed tomography
  • Precision medicine
  • Therapy response

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging

Cite this

Molecular Imaging and Precision Medicine : PET/Computed Tomography and Therapy Response Assessment in Oncology. / Sheikhbahaei, Sara; Mena, Esther; Pattanayak, Puskar; Taghipour, Mehdi; Solnes, Lilja B.; Subramaniam, Rathan M.

In: PET Clinics, Vol. 12, No. 1, 01.01.2017, p. 105-118.

Research output: Contribution to journalReview article

Sheikhbahaei, Sara ; Mena, Esther ; Pattanayak, Puskar ; Taghipour, Mehdi ; Solnes, Lilja B. ; Subramaniam, Rathan M. / Molecular Imaging and Precision Medicine : PET/Computed Tomography and Therapy Response Assessment in Oncology. In: PET Clinics. 2017 ; Vol. 12, No. 1. pp. 105-118.
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