Molecular modeling of cardiac glycoside binding by the human sequence monoclonal antibody 1B3

Medicine & Life Sciences

• Cardiac Glycosides 92%
• Digoxin 80%
• Monoclonal Antibodies 49%
• Complementarity Determining Regions 40%
• Hydrogen Bonding 23%
• Structural Models 22%
• Ligands 20%
• digitoxose 20%
• Cardenolides 16%
• Steroids 14%
• Light 13%
• Quantitative Structure-Activity Relationship 13%
• Structure-Activity Relationship 11%
• Hydrophobic and Hydrophilic Interactions 10%
• Hydroxyl Radical 10%
• Sugars 9%
• Amino Acid Sequence 8%
• Carbohydrates 8%
• Binding Sites 7%
• Amino Acids 6%
• Antigens 6%
• Pharmaceutical Preparations 4%

Chemical Compounds

• Cardiac Glycoside 100%
• Digoxin 96%
• Molecular Modeling 61%
• Digitoxose 18%
• Steroid 17%
• Cardenolide 16%
• Kd 14%
• Hydrogen Bond 11%
• Acetyl Group 11%
• QSAR Study 10%
• Amino Acid Sequence 8%
• Cyclic Structure 8%
• Amino-Acid Residue 8%
• Ligand 8%
• Structure-Activity Relationship 8%
• Antigen 8%
• Binding Site 6%
• Force 6%
• Environment 5%
• Modification 5%
• Drug 5%
• Crystal Structure 4%