TY - JOUR
T1 - Molecular tools for the detection and characterization of bacterial infections
T2 - A review
AU - Muthukumar, Alagarraju
AU - Zitterkopf, Nicole L.
AU - Payne, Deborah
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2008
Y1 - 2008
N2 - Bacterial infections, especially drug-resistant infections, continue to cause public health problems. While culture methods currently serve as the reference method for detecting and characterizing most bacterial infections, new molecular techniques provide the means for rapid, specific, and sensitive detection of pathogenic bacteria. Previously, molecular detection of bacteria focused on difficult-to-culture or slow-growing bacteria; however, with the advent of more robust instrumentation, molecular assays are used to identify, detect, and track the epidemiology of drug-resistant bacteria and hospital-acquired bacteria. This review discusses select nucleic acid tests (NATs), nucleic acid amplification tests (NAATs), and their applications for detecting and characterizing bacterial pathogens.
AB - Bacterial infections, especially drug-resistant infections, continue to cause public health problems. While culture methods currently serve as the reference method for detecting and characterizing most bacterial infections, new molecular techniques provide the means for rapid, specific, and sensitive detection of pathogenic bacteria. Previously, molecular detection of bacteria focused on difficult-to-culture or slow-growing bacteria; however, with the advent of more robust instrumentation, molecular assays are used to identify, detect, and track the epidemiology of drug-resistant bacteria and hospital-acquired bacteria. This review discusses select nucleic acid tests (NATs), nucleic acid amplification tests (NAATs), and their applications for detecting and characterizing bacterial pathogens.
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U2 - 10.1309/M6MBU1KGP0FF1C00
DO - 10.1309/M6MBU1KGP0FF1C00
M3 - Review article
AN - SCOPUS:59849083330
VL - 39
SP - 430
EP - 436
JO - Laboratory Medicine
JF - Laboratory Medicine
SN - 0007-5027
IS - 7
ER -