Monitoring early tumor response to vascular targeted therapy using super-resolution ultrasound imaging

Debabrata Ghosh, Fangyuan Xiong, Robert Mattrey, Shashank Sirsi, Kenneth Hoyt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Abstract

The standard-of-care for evaluating breast tumor response to chemotherapeutic drug treatment remains the assessment of a tumor size change weeks after therapy begins. However, the tumor microenvironment is known to change drastically before any detectable change in physical size manifests. New clinical tools that can help determine early tumor response are urgently needed so we can both maximize the benefit of an effective therapeutic strategy and minimize the use of drugs that do not improve patient prognosis. To that end, the goal of this research project was to evaluate the utility of super-resolution ultrasound (SR-US) imaging for detecting the early tumor response (or lack thereof) to antiangiogenic-targeted therapy.

Original languageEnglish (US)
Title of host publication2017 IEEE International Ultrasonics Symposium, IUS 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781538633830
DOIs
StatePublished - Oct 31 2017
Event2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States
Duration: Sep 6 2017Sep 9 2017

Other

Other2017 IEEE International Ultrasonics Symposium, IUS 2017
CountryUnited States
CityWashington
Period9/6/179/9/17

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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    Ghosh, D., Xiong, F., Mattrey, R., Sirsi, S., & Hoyt, K. (2017). Monitoring early tumor response to vascular targeted therapy using super-resolution ultrasound imaging. In 2017 IEEE International Ultrasonics Symposium, IUS 2017 [8092246] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2017.8092246