Monoclonal antibody-defined lymphocyte subsets in normal Nigerians

Research output: Contribution to journalArticle

Abstract

Lymphocyte subsets using monoclonal antibodies have hitherto not been reported in normal Nigerian subjects. In all 8 subjects, the average number of lymphocytes showed a clear rhythmicity with higher values in the morning (8 AM) than in the afternoon (2 PM). The time of day variation in circulating lymphocytes appears to affect T cells rather than B cells. The absolute numbers of OKT4+ cells at 8 AM was significantly higher than at 2 PM (p < 0.05). It would appear that the OKT4+ cells are largely responsible for the time of day variation in peripheral blood lymphocytes, owing probably to a greater sensitivity to changes in plasma cortisol levels.

Original languageEnglish (US)
Pages (from-to)977-981
Number of pages5
JournalAngiology
Volume40
Issue number11
StatePublished - 1989

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Lymphocyte Subsets
Monoclonal Antibodies
Lymphocytes
Lymphocyte Count
Periodicity
Hydrocortisone
B-Lymphocytes
Cell Count
T-Lymphocytes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Monoclonal antibody-defined lymphocyte subsets in normal Nigerians. / Adedeji, M. O.

In: Angiology, Vol. 40, No. 11, 1989, p. 977-981.

Research output: Contribution to journalArticle

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