Motion tracking and electromyography assist the removal of mirror hand contributions to fNIRS images acquired during a finger tapping task performed by children with cerebral palsy

Nathan Hervey, Bilal Khan, Laura Shagman, Fenghua Tian, Mauricio R. Delgado, Kirsten Tulchin-Francis, Angela Shierk, Linsley Smith, Dahlia Reid, Nancy J. Clegg, Hanli Liu, Duncan MacFarlane, George Alexandrakis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Functional neurological imaging has been shown to be valuable in evaluating brain plasticity in children with cerebral palsy (CP). In recent studies it has been demonstrated that functional near-infrared spectroscopy (fNIRS) is a viable and sensitive method for imaging motor cortex activities in children with CP. However, during unilateral finger tapping tasks children with CP often exhibit mirror motions (unintended motions in the non-tapping hand), and current fNIRS image formation techniques do not account for this. Therefore, the resulting fNIRS images contain activation from intended and unintended motions. In this study, cortical activity was mapped with fNIRS on four children with CP and five controls during a finger tapping task. Finger motion and arm muscle activation were concurrently measured using motion tracking cameras and electromyography (EMG). Subject-specific regressors were created from motion capture and EMG data and used in a general linear model (GLM) analysis in an attempt to create fNIRS images representative of different motions. The analysis provided an fNIRS image representing activation due to motion and muscle activity for each hand. This method could prove to be valuable in monitoring brain plasticity in children with CP by providing more consistent images between measurements. Additionally, muscle effort versus cortical effort was compared between control and CP subjects. More cortical effort was required to produce similar muscle effort in children with CP. It is possible this metric could be a valuable diagnostic tool in determining response to treatment.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8565
DOIs
StatePublished - 2013
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: Feb 2 2013Feb 7 2013

Other

OtherPhotonic Therapeutics and Diagnostics IX
CountryUnited States
CitySan Francisco, CA
Period2/2/132/7/13

Fingerprint

electromyography
Electromyography
Near infrared spectroscopy
Near-Infrared Spectroscopy
Cerebral Palsy
Fingers
Mirrors
Hand
infrared spectroscopy
mirrors
Muscle
muscles
Chemical activation
Muscles
Plasticity
Brain
activation
plastic properties
brain
Imaging techniques

Keywords

  • Cerebral palsy
  • Functional near-infrared spectroscopy
  • General linear model
  • Rehabilitation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Motion tracking and electromyography assist the removal of mirror hand contributions to fNIRS images acquired during a finger tapping task performed by children with cerebral palsy. / Hervey, Nathan; Khan, Bilal; Shagman, Laura; Tian, Fenghua; Delgado, Mauricio R.; Tulchin-Francis, Kirsten; Shierk, Angela; Smith, Linsley; Reid, Dahlia; Clegg, Nancy J.; Liu, Hanli; MacFarlane, Duncan; Alexandrakis, George.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013. 856563.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hervey, N, Khan, B, Shagman, L, Tian, F, Delgado, MR, Tulchin-Francis, K, Shierk, A, Smith, L, Reid, D, Clegg, NJ, Liu, H, MacFarlane, D & Alexandrakis, G 2013, Motion tracking and electromyography assist the removal of mirror hand contributions to fNIRS images acquired during a finger tapping task performed by children with cerebral palsy. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8565, 856563, Photonic Therapeutics and Diagnostics IX, San Francisco, CA, United States, 2/2/13. https://doi.org/10.1117/12.2004352
Hervey, Nathan ; Khan, Bilal ; Shagman, Laura ; Tian, Fenghua ; Delgado, Mauricio R. ; Tulchin-Francis, Kirsten ; Shierk, Angela ; Smith, Linsley ; Reid, Dahlia ; Clegg, Nancy J. ; Liu, Hanli ; MacFarlane, Duncan ; Alexandrakis, George. / Motion tracking and electromyography assist the removal of mirror hand contributions to fNIRS images acquired during a finger tapping task performed by children with cerebral palsy. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013.
@inproceedings{9073962aef0143dbb7334c6e1b580c78,
title = "Motion tracking and electromyography assist the removal of mirror hand contributions to fNIRS images acquired during a finger tapping task performed by children with cerebral palsy",
abstract = "Functional neurological imaging has been shown to be valuable in evaluating brain plasticity in children with cerebral palsy (CP). In recent studies it has been demonstrated that functional near-infrared spectroscopy (fNIRS) is a viable and sensitive method for imaging motor cortex activities in children with CP. However, during unilateral finger tapping tasks children with CP often exhibit mirror motions (unintended motions in the non-tapping hand), and current fNIRS image formation techniques do not account for this. Therefore, the resulting fNIRS images contain activation from intended and unintended motions. In this study, cortical activity was mapped with fNIRS on four children with CP and five controls during a finger tapping task. Finger motion and arm muscle activation were concurrently measured using motion tracking cameras and electromyography (EMG). Subject-specific regressors were created from motion capture and EMG data and used in a general linear model (GLM) analysis in an attempt to create fNIRS images representative of different motions. The analysis provided an fNIRS image representing activation due to motion and muscle activity for each hand. This method could prove to be valuable in monitoring brain plasticity in children with CP by providing more consistent images between measurements. Additionally, muscle effort versus cortical effort was compared between control and CP subjects. More cortical effort was required to produce similar muscle effort in children with CP. It is possible this metric could be a valuable diagnostic tool in determining response to treatment.",
keywords = "Cerebral palsy, Functional near-infrared spectroscopy, General linear model, Rehabilitation",
author = "Nathan Hervey and Bilal Khan and Laura Shagman and Fenghua Tian and Delgado, {Mauricio R.} and Kirsten Tulchin-Francis and Angela Shierk and Linsley Smith and Dahlia Reid and Clegg, {Nancy J.} and Hanli Liu and Duncan MacFarlane and George Alexandrakis",
year = "2013",
doi = "10.1117/12.2004352",
language = "English (US)",
isbn = "9780819493347",
volume = "8565",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Motion tracking and electromyography assist the removal of mirror hand contributions to fNIRS images acquired during a finger tapping task performed by children with cerebral palsy

AU - Hervey, Nathan

AU - Khan, Bilal

AU - Shagman, Laura

AU - Tian, Fenghua

AU - Delgado, Mauricio R.

AU - Tulchin-Francis, Kirsten

AU - Shierk, Angela

AU - Smith, Linsley

AU - Reid, Dahlia

AU - Clegg, Nancy J.

AU - Liu, Hanli

AU - MacFarlane, Duncan

AU - Alexandrakis, George

PY - 2013

Y1 - 2013

N2 - Functional neurological imaging has been shown to be valuable in evaluating brain plasticity in children with cerebral palsy (CP). In recent studies it has been demonstrated that functional near-infrared spectroscopy (fNIRS) is a viable and sensitive method for imaging motor cortex activities in children with CP. However, during unilateral finger tapping tasks children with CP often exhibit mirror motions (unintended motions in the non-tapping hand), and current fNIRS image formation techniques do not account for this. Therefore, the resulting fNIRS images contain activation from intended and unintended motions. In this study, cortical activity was mapped with fNIRS on four children with CP and five controls during a finger tapping task. Finger motion and arm muscle activation were concurrently measured using motion tracking cameras and electromyography (EMG). Subject-specific regressors were created from motion capture and EMG data and used in a general linear model (GLM) analysis in an attempt to create fNIRS images representative of different motions. The analysis provided an fNIRS image representing activation due to motion and muscle activity for each hand. This method could prove to be valuable in monitoring brain plasticity in children with CP by providing more consistent images between measurements. Additionally, muscle effort versus cortical effort was compared between control and CP subjects. More cortical effort was required to produce similar muscle effort in children with CP. It is possible this metric could be a valuable diagnostic tool in determining response to treatment.

AB - Functional neurological imaging has been shown to be valuable in evaluating brain plasticity in children with cerebral palsy (CP). In recent studies it has been demonstrated that functional near-infrared spectroscopy (fNIRS) is a viable and sensitive method for imaging motor cortex activities in children with CP. However, during unilateral finger tapping tasks children with CP often exhibit mirror motions (unintended motions in the non-tapping hand), and current fNIRS image formation techniques do not account for this. Therefore, the resulting fNIRS images contain activation from intended and unintended motions. In this study, cortical activity was mapped with fNIRS on four children with CP and five controls during a finger tapping task. Finger motion and arm muscle activation were concurrently measured using motion tracking cameras and electromyography (EMG). Subject-specific regressors were created from motion capture and EMG data and used in a general linear model (GLM) analysis in an attempt to create fNIRS images representative of different motions. The analysis provided an fNIRS image representing activation due to motion and muscle activity for each hand. This method could prove to be valuable in monitoring brain plasticity in children with CP by providing more consistent images between measurements. Additionally, muscle effort versus cortical effort was compared between control and CP subjects. More cortical effort was required to produce similar muscle effort in children with CP. It is possible this metric could be a valuable diagnostic tool in determining response to treatment.

KW - Cerebral palsy

KW - Functional near-infrared spectroscopy

KW - General linear model

KW - Rehabilitation

UR - http://www.scopus.com/inward/record.url?scp=84878186960&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878186960&partnerID=8YFLogxK

U2 - 10.1117/12.2004352

DO - 10.1117/12.2004352

M3 - Conference contribution

AN - SCOPUS:84878186960

SN - 9780819493347

VL - 8565

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -